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Volume 29, Number 8—August 2023
Research Letter

Six Extensively Drug-Resistant Bacteria in an Injured Soldier, Ukraine

Patrick T. Mc Gann, Francois Lebreton, Brendan T. Jones, Henry D. Dao, Melissa J. Martin, Messiah J. Nelson, Ting Luo, Andrew C. Wyatt, Jason R. Smedberg, Joanna M. Kettlewell, Brain M. Cohee, Joshua S. Hawley-Molloy, and Jason W. Bennett
Author affiliations: Multidrug-Resistant Organism Repository and Surveillance Network, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA (P.T. Mc Gann, F. LeBreton, B.T. Jones, H.D. Dao, M.J. Martin, M.J. Nelson, T. Luo, J.W. Bennett); Landstuhl Regional Medical Center, Landstuhl, Germany (A.C. Wyatt, J.R. Smedberg, J.M. Kettlewell, J.S. Hawley-Malloy); 512th Field Hospital, Rhine Ordinance Barracks, Germany (B.M. Cohee)

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Table

Characteristics of 6 isolates cultured from an injured service member from Ukraine*

MRSN ID Species ST† Antimicrobial resistance genes‡
110819 Acinetobacter baumannii 78 aph(3′)-Via, aac(6')-Ian, armA, aadA5, ant(3′′)-IIa, blaOXA-23, blaOXA-72, blaOXA-90, blaADC-152, blaCTX-M-115, blaCARB-16, catA1, mph(E), msr(E), sul1, sul2
110818 Pseudomonas aeruginosa 357 aac(6')-Il, aph(3′)-IIb, aadA1, blaOXA-10, blaOXA-846, blaPDC-11, blaVEB-9, catB7, sul1, tet(A), dfrB2
110817 P. aeruginosa 773 aph(3′)-IIb, aadA11, blaNDM-1, blaPDC-16, blaOXA-395, catB7, qnrVC1, rmtB4, sul1, tet(G)
110606§ P. aeruginosa 1047 aac(6')-Ib3, aph(3′)-IIb, aph(3′′)-Ib, aph(6)-Id, blaIMP-1, blaOXA-10, blaOXA-488, blaPDC-12, catB7, sul1
110821 Klebsiella pneumoniae 395 aac(6')-Ib-cr5, aph(3′)-VI, ant(2′′)-Ia, aadA1, armA, blaNDM-1, blaOXA-48, blaCTX-M-15, blaOXA-1, blaSHV-11, blaTEM-1, catA1, dfrA1, dfrA5, fosA, mph(A), mph(E), msr(E), oqxA, oqxB, qnrS1, sul1, sul2, tet(A)
110820 Enterococcus faecium 117 aac(6')-Ie, aacA-ENT1, aph(2′′)-Ia, catA7, dfrG, erm(B), msr(C), vanA (operon)

*Bold indicates high-impact genes. MRSN, The Multidrug-Resistant Organism Repository and Surveillance Network; ID, identification; ST, sequence type.

†In silico–derived multilocus STs.

‡In silico–derived antimicrobial resistance gene content generated using MIGHT, a customized script wrapping ARIBA (https://github.com/sanger-pathogens/ariba) and AMRfinder (https://github.com/ncbi/amr).

§Blood culture isolate.

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References
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Page created: June 29, 2023
Page updated: July 20, 2023
Page reviewed: July 20, 2023
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