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Volume 29, Number 9—September 2023

Dispatch

Population-Based Serologic Survey of Vibrio cholerae Antibody Titers before Cholera Outbreak, Haiti, 2022

Christy H. Clutter1Comments to Author , Molly B. Klarman1, Youseline Cajusma, Emilee T. Cato, Md. Abu Sayeed, Lindsey Brinkley, Owen Jensen, Chantale Baril, V. Madsen Beau De Rochars, Andrew S. Azman, Maureen T. Long, Derek Cummings, Daniel T. Leung2, and Eric J. Nelson2
Author affiliations: University of Utah, Salt Lake City, Utah, USA (C.H. Clutter, O. Jensen, D.T. Leung); University of Florida, Gainesville, Florida, USA (M.B. Klarman, Y. Cajusma, E.T. Cato, M.A. Sayeed, L. Brinkley, V.M. Beau De Rochars, M.T. Long, D. Cummings, E.J. Nelson); Université d'État d'Haïti, Port au Prince, Haiti (C. Baril); Johns Hopkins University, Baltimore, Maryland, USA (A.S. Azman)

Main Article

Figure 2

Antibody titers by age, vaccination status, and previous history of infection among participants in a serologic study conducted before a cholera outbreak in Haiti, 2022. We compared antibody titers for lipopolysaccharide (LPS) and cholera toxin subunit B (CtxB) between children <5 years of age (n = 112) and adults and children >5 years of age for LPS IgG (A), LPS IgA (B), CtxB IgG (C), and CtxB IgA (D). We made statistical comparisons between the <5- and ≥5-year age groups using an unpaired 2-tailed Student t test. Individual year-by-year comparisons were compared using 1-way analysis of variance. Horizontal lines indicate medians; error bars indicate interquartile ranges. Significant p values are indicated.

Figure 2. Antibody titers by age, vaccination status, and previous history of infection among participants in a serologic study conducted before a cholera outbreak in Haiti, 2022. We compared antibody titers for lipopolysaccharide (LPS) and cholera toxin subunit B (CtxB) between children <5 years of age (n = 112) and adults and children >5 years of age for LPS IgG (A), LPS IgA (B), CtxB IgG (C), and CtxB IgA (D). We made statistical comparisons between the <5- and ≥5-year age groups using an unpaired 2-tailed Student t test. Individual year-by-year comparisons were compared using 1-way analysis of variance. Horizontal lines indicate medians; error bars indicate interquartile ranges. Significant p values are indicated.

Main Article

1These first authors contributed equally to this article.

2These senior authors contributed equally to this article.

Page created: July 10, 2023
Page updated: August 20, 2023
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