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Volume 29, Number 9—September 2023
Research Letter

Rickettsial Disease Outbreak, Mexico, 2022

Ricardo J. Estrada-Mendizabal, Oscar Tamez-RiveraComments to Author , Emelina Hinojosa Vela, Paulina Blanco-Murillo, Cordelia Alanis-Garza, Jaime Flores-Gouyonnet, Jessica Suhail Sauceda Garza, Gloria Yolanda Carranza Medina, Lilia Elida García Rodriguez, and Alma Rosa Marroquin Escamilla
Author affiliations: Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Monterrey, Mexico (R.J. Estrada-Mendizabal, O. Tamez-Rivera, P. Blanco-Murillo, C. Alanis-Garza); Secretary of Health of Nuevo Leon, Monterrey (E. Hinojosa Vela, J.S. Sauceda Garza, G.Y. Carranza Medina, L.E. Garcia Rodriguez, A.R. Marroquin Escamilla); Autonomous University of San Luis Potosi, San Luis Potosi, Mexico (J. Flores-Gouyonnet)

Main Article

Table

Clinical and paraclinical characteristics of patients with rickettsioses during outbreak in Neuvo Leon, Mexico, 2022

Characteristic
 Total, n = 57
 No. (%) patients
 p value†
Cured, n = 21
 Died, n = 36
Patient age, y 0.106
<4 8 1 (1.7) 7 (12.2)
4–12 28 12 (21) 16 (28)
13–18 8 1 (1.7) 7 (12.2)
>18
 13
 7 (12.2)
 6 (10.5)
Patient sex 0.768
F 34 12 (21) 22 (38.5)
M
 23
 9 (15.7)
 14 (24.5)
Clinical signs‡ n = 48 n = 14 n = 34
Anemia 0.012
Yes 32 11 (22.9) 21 (43.7)
No 16 3 (6.2) 13 (27)
Thrombocytopenia 0.007
Yes 47 13 (27) 34 (70.8)
No 1 1 (2) 0
Leukocytosis 0.01
Yes 17 3 (6.2) 14 (29.1)
No 31 11 (22.9) 20 (41.6)
Leukopenia 0.014
Yes 4 2 (4.1) 2 (4.1)
No
 44
 12 (25)
 32 (66.6)
Treatment with doxycycline 0.074
Yes 52 21 (36.8) 31 (54.3)
No§
 5
 0
 5 (8.7)
Time to treatment initiation, h n = 52 n = 21 n = 31 0.007
≤24 4 4 (7.6) 0
>24 48 17 (32.6) 31 (59.6)

*n values within columns indicate number of patients in category. †By χ2 test. Bold indicates statistical significance. ‡Anemia: female, hemoglobin <11.6 g/dL; male, hemoglobin <13.2 g/dL). Thrombocytopenia: female, platelets <157 × 109/L; male, platelets <135 × 109/L. Leukocytosis: leukocytes >9.6 × 109 cells/L. Leukopenia: leukocytes <3.4 × 109 cells/L. §Five patients died before treatment and had their diagnosis confirmed by autopsy.

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Page created: August 09, 2023
Page updated: August 20, 2023
Page reviewed: August 20, 2023
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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