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Volume 29, Number 9—September 2023
Dispatch

Emergence of GII.4 Sydney[P16]-like Norovirus-Associated Gastroenteritis, China, 2020–2022

Yuanyun Ao1Comments to Author , Lijuan Lu1, and Jin XuComments to Author 
Author affiliations: Children's Hospital of Fudan University, Shanghai, China (Y. Ao, L. Lu, J. Xu); Shanghai Institute of Infectious Disease and Biosecurity of Fudan University, Shanghai, China (J. Xu).

Main Article

Table

Comparisons of sociodemographic and clinical characteristics between GII.4 Sydney[P16] norovirus and GII.4 Sydney[P31]/GII.3[P12] norovirus infection in norovirus–positive children, Shanghai, China, January 2016–March 2022*

Characteristic GII.4 Sydney[P16] GII.4 Sydney[P31] p value† GII.3[P12] p value‡
Total no. patients
 63
 120
47
Median patient age, mo (IQR)
 21.5 (15–50.3)
 12 (9–19.3)
 <0.0001§
 12 (8–26.75)
 0.004§
Age range, mo
<12 9 (14.3) 47 (39.2) 0.001 18 (38.3) 0.004
12–36 31 (49.2) 63 (52.5) 0.672¶ 19 (40.4) 0.360¶
>36
23 (36.5)
 10 (8.3)
 <0.001
 10 (21.3)
 0.085¶
F:M ratio
 0.58:1
 0.5:1
 0.744#
 0.48:1
 0.688#
Signs/symptoms
Total no. patients with signs/symptoms 60 112 NA 44 NA
Diarrhea 45 (75.0) 93 (83.0) 0.586¶ 33 (75.0) 0.579¶
Duration <5 d 33 (73.3) 64 (68.8) 0.821¶ 26 (78.8) 0.837¶
Duration >5 d 12 (26.7) 29 (31.2) 0.687¶ 7 (21.2) 0.664¶
Vomiting 35 (58.3) 40 (35.7) <0.001 17 (38.6) 0.047
Fever 18 (30.0) 20 (17.9) 0.067¶ 17 (38.6) 0.357¶
Abdominal cramps 9 (15) 2 (1.8) 0.02¶ 6 (13.6) 0.845¶

*Values are no. (%) patients except as indicated. Bold indicates statistical significance. NA, not applicable †Denotes comparison between GII.4 Sydney[P16] and GII.4 Sydney[P31]. ‡Indicates comparison between GII.4 Sydney[P16] and GII.3[P12]. §By χ2 test. ¶For the comparison of the median age between groups; calculated by Mann-Whitney U-test. #By Fisher exact test.

Main Article

1These authors contributed equally to this article.

Page created: June 29, 2023
Page updated: August 20, 2023
Page reviewed: August 20, 2023
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