Volume 29, Number 9—September 2023
Dispatch
High Prevalence of Candida auris Colonization during Protracted Neonatal Unit Outbreak, South Africa
Liliwe Shuping
, Tsidiso G. Maphanga, Serisha D. Naicker, Ruth Mpembe, Nqobile Ngoma, Sithembiso Velaphi, Firdose Nakwa, Jeannette Wadula, Prenika Jaglal, and Nelesh P. Govender
, Tsidiso G. Maphanga, Serisha D. Naicker, Ruth Mpembe, Nqobile Ngoma, Sithembiso Velaphi, Firdose Nakwa, Jeannette Wadula, Prenika Jaglal, and Nelesh P. Govender
Table 2
Diagnostic accuracy measures for a direct SYBR PrimeScript RT-PCR compared with culture (standard) during a Candida auris colonization survey in neonatal unit of Chris Hani Baragwanath Academic Hospital, Johannesburg, South Africa, November 2, 2021*
| Neonatal unit | Sensitivity | Specificity | Positive predictive value | Negative predictive value | Diagnostic accuracy |
|---|---|---|---|---|---|
| Intensive care | 60 (26–88) | 100 (16–100) | 100 (54–100) | 33 (4.0–78) | 67 (35–90) |
| Transitional care | 57 (29–82) | 100 (89–100) | 100 (63–100) | 84 (69–94) | 87 (74–95) |
| High care surgical | 67 (22–96) | 75 (19–99) | 80 (28–9) | 60 (15–95) | 70 (35–93) |
| High care | 26 (11–46) | 100 (95–100) | 100 (59–93) | 78 (67–86) | 79 (70–87) |
| Kangaroo mother and child care |
50 (12–88) |
100 (86–100) |
100 (29–100) |
89 (71–98) |
90 (73–98) |
| Overall | 44 (32–58) | 99 (96–100) | 97 (82–100) | 79 (72–85) | 81 (74–85) |
*Values in parentheses are 95% CIs. One patient had a positive RT-PCR result but a negative culture. A heavy growth of Staphylococcus aureus from this patient’s sample could have overgrown C. auris. RT-PCR, reverse transcription PCR.
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Page updated: August 20, 2023
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