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Volume 29, Number 9—September 2023
Dispatch

Laboratory Diagnosis of Mpox, Central African Republic, 2016–2022

Sandra Garba-Ouangole1, Josephine Bourner1Comments to Author , Festus Mbrenga, Ella Gonofio, Benjamin Selekon, Alexandre Manirakiza, Ernest Kalthan, Christian Malaka, Yap Boum, Piero Olliaro2, and Emmanuel Nakouné2
Author affiliations: Institut Pasteur de Bangui, Bangui, Central African Republic (S. Garba-Ouangole, F. Mbrenga, E. Gonofio, C. Malaka, Y. Boum II, E. Nakouné); International Severe Acute Respiratory and Emerging Infection Consortium, Pandemic Sciences Institute, University of Oxford, Oxford, UK (J. Bourner); Ministry of Health and Population, Bangui (B. Selekon, A. Manirakiza, E. Kalthan)

Main Article

Table 2

Cycle threshold values obtained using G2RG and C3L PCR primers on different specimens in a study assessing laboratory diagnosis of mpox, Central African Republic, 2016–2022*

Specimen type MPXV (G2RG) MPXV (C3L) VZV
Blood 32.11 (29.12–35.45) 32.93 (30.25–35.94) 34.41 (31.38–36.01)
Active lesion 18.92 (17.42–23.43) 19.61 (18.05–23.57) 19.23 (17.69–20.82)
Scab 18.07 (16.19–19.82) 18.13 (16.46–21.46) 15.78 (13.63–18.42)
Oropharyngeal 30.15 (28.04–32.56) 28.19 (26.79–29.59) 34.31 (32.95–35.67)

*Data are median cycle threshold value (interquartile range). C3L, clade I–specific primer; G2RG, generic primer; MPXV, monkeypox virus; VZV, varicella–zoster virus.

Main Article

1These first authors contributed equally to this article.

2These senior authors contributed equally to this article.

Page created: July 05, 2023
Page updated: August 20, 2023
Page reviewed: August 20, 2023
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