Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link

Volume 3, Number 3—September 1997

Synopsis

Borna Disease Virus Infection in Animals and Humans

Jürgen A. Richt*Comments to Author , Isolde Pfeuffer*, Matthias Christ*, Knut Frese†, Karl Bechter‡, and Sibylle Herzog*
Author affiliations: *Institut für Virologie, Giessen, Germany; †Institut für Veterinär-Pathologie, Giessen, Germany; and ‡Universität Ulm, Günzburg, Germany

Main Article

Table 1

Adoptive transfer of Borna disease virus (BDV) TH1 cells before and after BDV infection

Group CY treatment Transfer of TH1-cells Clinical BD
Control yes day +10 no
BDV yes no no
BDV no day +10 yes
BDV yes day +3 yes
BDV yes day +10 yes
BDV no day -25 and -5 no

Four-week-old Lewis rats were inoculated intracerebrally with BDV; some rats were treated with cyclophosphamide (CY) (150 mg/kg) for immunosuppression 24 hours later. Animals were intravenously injected with >2x106 BDV-specific TH1 cells on the indicated days, either before (-) or after (+) infection with BDV.

Main Article

Page created: December 21, 2010
Page updated: December 21, 2010
Page reviewed: December 21, 2010
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external