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Volume 30, Number 1—January 2024
Research

Costs of Digital Adherence Technologies for Tuberculosis Treatment Support, 2018–2021

Ntwali Placide Nsengiyumva, Amera Khan, Maricelle Ma. Tarcela S. Gler, Mariecef L. Tonquin, Danaida Marcelo, Mark C. Andrews, Karine Duverger, Shahriar Ahmed, Tasmia Ibrahim, Sayera Banu, Sonia Sultana, Mona Lisa Morales, Andre Villanueva, Egwumo Efo, Baraka Onjare, Cristina Celan, and Kevin SchwartzmanComments to Author 
Author affiliations: McGill International Tuberculosis Centre and Research Institute, McGill University Health Centre, Montreal, Quebec, Canada (N.P. Nsengiyumva, K. Schwartzman); Stop TB Partnership, Geneva, Switzerland (A. Khan); De La Salle Medical and Health Sciences Institute, Makati City, Philippines (M.M.T.S. Gler, M.L. Tonquin, D. Marcelo); Health Through Walls, Port au Prince, Haiti (M.C. Andrews, K. Duverger); icddr,b, Dhaka, Bangladesh (S. Ahmed, T. Ibrahim, S. Banu, S. Sultana); KNCV, Manila, Philippines (M.L. Morales, A. Villanueva); KNCV, Dar es Salaam, Tanzania (E. Efo, B. Onjare); Center for Health Policies and Studies, Chisinau, Moldova (C. Celan)

Main Article

Table 3

Digital adherence technologies compared with directly observed therapy costs*

Cost 99DOTS sites, US$
VOT sites, US$
Bangladesh, healthcare facility Philippines, health care facility Tanzania, home Haiti, prison Philippines, healthcare facility or home
Moldova, health facility
DS-TB DR-TB All TB
Crude estimate for DOT cost for the standard of care derived from the costing tool
Hourly wage of person offering DOT support 0.83 1.40 0.00 4.60 11.20 11.20 11.20 2.88
Duration of DOT visit, min
45
45
0

45
15
15
15
2
Total per patient cost
DOT cost from study data 74 176 0 414 336 504 427 17
DOT cost from the literature 36 (22) 155 (23) 89 (24) 49 (25) 166 (23)
Annuitized cost of DAT 81 92 163 1,060 172 254 211 495
Variable DAT costs only
60
83
160

702
151
222
185
247
Incremental per patient cost for the DAT versus standard of care
Study data as comparator† 7 –84 163 646 –164 –250 –216 478
Prior published data as comparator‡
45
–63
74

1,011



329
Incremental per patient cost for the DAT using variable costs only versus standard of care, assuming fixed costs are already sunk
Study data as comparator† –14 –93 160 288 –185 –282 –242 230
Prior published data as comparator‡ 24 –72 71 653 81

*DAT, digital adherence technologies; DOT, directly observed therapy; –, no prior published data available for comparison. †Negative incremental costs indicate savings for the DAT relative to standard of care. ‡There is no available literature documenting the cost of DOT in Moldova; therefore, we did not calculate incremental costs when published literature was the comparator.

Main Article

Page created: October 31, 2023
Page updated: December 20, 2023
Page reviewed: December 20, 2023
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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