Macacine alphaherpesvirus 1 (B Virus) Infection in Humans, Japan, 2019
Souichi Yamada, Harutaka Katano, Yuko Sato, Tadaki Suzuki, Akihiko Uda, Keita Ishijima, Motoi Suzuki, Daigo Yamada, Shizuko Harada, Hitomi Kinoshita, Phu Hoang Anh Nguyen, Hideki Ebihara, Ken Maeda, Masayuki Saijo, and Shuetsu Fukushi
Author affiliations: National Institute of Infectious Diseases, Tokyo, Japan (S. Yamada, H. Katano, Y. Sato, T. Suzuki, A. Uda, K. Ishijima, M. Suzuki, S. Harada, H. Kinoshita, P.H.A. Nguyen, H. Ebihara, K. Maeda, M. Saijo, S. Fukushi); Ministry of Health, Labor and Welfare, Tokyo (D. Yamada); Health and Welfare Bureau, Sapporo, Japan (M. Saijo)
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Figure 1
Figure 1. Brain biopsy from patient (patient 2) with Macacine alphaherpesvirus 1 (herpes B virus) infection, Japan, 2019. A–C) Inflammatory cell infiltration and hemorrhage observed around blood vessels in the cerebellar white matter. Arrows indicate nuclear inclusion bodies (B, C). Hematoxylin and eosin stain. D, E) Immunohistochemical analysis using B virus gB mouse monoclonal (clone 19B6) (D) and an B virus rabbit polyclonal (E) antibodies as the primary antibodies. Original magnification × 200 for all images.
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