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Volume 30, Number 1—January 2024
Dispatch

Hantavirus Disease Cluster Caused by Seoul Virus, Germany

Jörg HofmannComments to Author , Rainer G. Ulrich, Calvin Mehl, Stephan Drewes, Jutta Esser, Martin Loyen, Heinz Zeichhardt, Konrad Schoppmeyer, Lioba Essen, Wolfgang Güthoff, and Detlev H. Krüger
Author affiliations: Charité–Universitätsmedizin Berlin, Berlin, Germany (J. Hofmann, D.H. Kruger); German Centre for Infection Research (DZIF), Partner Site Hamburg-Lübeck-Borstel-Riems, Greifswald-Insel Riems, Germany (R.G. Ulrich, C. Mehl); Friedrich-Loeffler-Institut, Greifswald-Insel Riems (R.G. Ulrich, C. Mehl, S. Drewes); Laborarztpraxis Osnabrück, Georgsmarienhütte, Germany (J. Esser); Herz-Jesu Krankenhaus, Münster-Hiltrup, Germany (M. Loyen); INSTAND e.V., Society for Promoting Quality Assurance in Medical Laboratories, Düsseldorf, Germany (H. Zeichhardt); Institut für Qualitätssicherung in der Virusdiagnostik, Berlin (H. Zeichhardt); Euregio-Klinik, Nordhorn, Germany (K. Schoppmeyer); Maria-Josef-Hospital Greven, Greven, Germany (L. Essen); Gesellschaft für Biotechnologische Diagnostik mbH, Berlin (W. Güthoff)

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Figure

Phylogenetic tree of partial large segment Seoul virus sequences from humans and rats, Germany. Segments were 412-nt long, positions nt 2919–3330 based on reference sequence (KM948594_Cherwell_GBR_BR). The partial large segment Bayesian tree was reconstructed using 20 million generations and the Hasegawa-Kishino-Yano substitution model with gamma distribution and invariant sites. Single asterisks indicate sequences from this study, denoted by their GenBank accession numbers. Double asterisks indicate sequence from the imported Seoul virus case from Indonesia (9). Aa, Apodemus agrarius; BEL, Belgium; BEN, Benin; BR, breeder rat (includes feeder, lab, and pet rats); CAM, Cambodia; CHN, China; FRA, France; GBR, Great Britain; GER, Germany; HTNV, Hantaan virus; HU, human; IDN, Indonesia; KOR, Korea; L, large segment; NED, the Netherlands; Rn, Rattus norvegicus; RUS, Russia; SEN, Senegal; SEOV, Seoul virus; SWE, Sweden; UNK, unknown wild or breeder rat; USA, United States of America; VNM, Vietnam; WR, wild rat.

Figure. Phylogenetic tree of partial large segment Seoul virus sequences from humans and rats, Germany. Segments were 412-nt long, positions nt 2919–3330 based on reference sequence (KM948594_Cherwell_GBR_BR). The partial large segment Bayesian tree was reconstructed using 20 million generations and the Hasegawa-Kishino-Yano substitution model with gamma distribution and invariant sites. Single asterisks indicate sequences from this study, denoted by their GenBank accession numbers. Double asterisks indicate sequence from the imported Seoul virus case from Indonesia (9). Aa, Apodemus agrarius; BEL, Belgium; BEN, Benin; BR, breeder rat (includes feeder, lab, and pet rats); CAM, Cambodia; CHN, China; FRA, France; GBR, Great Britain; GER, Germany; HTNV, Hantaan virus; HU, human; IDN, Indonesia; KOR, Korea; L, large segment; NED, the Netherlands; Rn, Rattus norvegicus; RUS, Russia; SEN, Senegal; SEOV, Seoul virus; SWE, Sweden; UNK, unknown wild or breeder rat; USA, United States of America; VNM, Vietnam; WR, wild rat.

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