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Volume 30, Number 1—January 2024
Dispatch

Hantavirus Disease Cluster Caused by Seoul Virus, Germany

Jörg HofmannComments to Author , Rainer G. Ulrich, Calvin Mehl, Stephan Drewes, Jutta Esser, Martin Loyen, Heinz Zeichhardt, Konrad Schoppmeyer, Lioba Essen, Wolfgang Güthoff, and Detlev H. Krüger
Author affiliations: Charité–Universitätsmedizin Berlin, Berlin, Germany (J. Hofmann, D.H. Kruger); German Centre for Infection Research (DZIF), Partner Site Hamburg-Lübeck-Borstel-Riems, Greifswald-Insel Riems, Germany (R.G. Ulrich, C. Mehl); Friedrich-Loeffler-Institut, Greifswald-Insel Riems (R.G. Ulrich, C. Mehl, S. Drewes); Laborarztpraxis Osnabrück, Georgsmarienhütte, Germany (J. Esser); Herz-Jesu Krankenhaus, Münster-Hiltrup, Germany (M. Loyen); INSTAND e.V., Society for Promoting Quality Assurance in Medical Laboratories, Düsseldorf, Germany (H. Zeichhardt); Institut für Qualitätssicherung in der Virusdiagnostik, Berlin (H. Zeichhardt); Euregio-Klinik, Nordhorn, Germany (K. Schoppmeyer); Maria-Josef-Hospital Greven, Greven, Germany (L. Essen); Gesellschaft für Biotechnologische Diagnostik mbH, Berlin (W. Güthoff)

Main Article

Table 1

Clinical characteristics of patients infected with Seoul virus, Germany*

Criteria
 Patient 1
 Patient 2
 Patient 3
Domicile North Rhine-Westphalia North Rhine-Westphalia Lower Saxony
Sex M F M
Age, y 31 31 20
Duration of hospitalization, d 3 4 6
Initial fever, °C 40 39 40
Malaise, myalgia, chills, low-back pain, nausea Y Y Y
Serum creatinine elevation Y† N N
Thrombocytopenia Y Y† Y
CRP elevation Y Y Y
Liver enzyme elevation Y Y Y
GFR reduction Y Y N
Proteinuria Y Y Y
Microhematuria Y Y Y
Additional clinical findings Splenomegaly Splenomegaly Lung opacity

*CRP, C-reactive protein; GFR, glomerular filtration rate; LS, Lower Saxony; NRW, North Rhine-Westphalia. †Test result was at the cutoff between positive and negative.

Main Article

Page created: November 30, 2023
Page updated: December 20, 2023
Page reviewed: December 20, 2023
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