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Volume 30, Number 10—October 2024
Dispatch

Mpox Epidemiology and Vaccine Effectiveness, England, 2023

Hannah CharlesComments to Author , Katie Thorley, Charlie Turner, Kirsty F. Bennet, Nick Andrews, Marta Bertran, Sema Mandal, Gayatri Amirthalingam, Mary E. Ramsay, Hamish Mohammed, and Katy Sinka
Author affiliation: UK Health Security Agency, London, UK

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Table 2

Characteristics and risk factors for case-patients with mpox confirmed or highly probable according to specimens collected in 2023, England*

Variable No. (%), n = 128†
HIV status
Living with HIV 13 (10)
HIV negative 69 (54)
Taking HIV PrEP‡ 51 (74)
Not taking PrEP‡ 18 (26)
Unknown
 46 (36)
Modified Vaccinia Ankara–Bavarian Nordic vaccination status§
Vaccinated: >2 doses¶ 30 (23)
Vaccinated: 1 dose 20 (16)
Vaccinated: no. doses unknown 2 (2)
Unvaccinated 54 (42)
Unknown
 22 (17)
Childhood smallpox vaccination status
Vaccinated 4 (3)
Unknown
 124 (97)
Hospital admission
Yes 11 (9)
No 117 (91)
Unknown
Reporting attending events involving multiple sex partners
Yes 28 (22)
No 17 (13)
Unknown 83 (65)
Concurrent STI
Yes 24 (19)
No 28 (22)
Unknown 76 (59)

*Patients were median 36 years of age, range 19–70 years, interquartile range 29–24 years. PrEP, preexposure prophylaxis; STI, sexually transmitted infection. †Unless otherwise stated, denominators are 128; denominators for percentage calculations are HIV-negative persons. ‡We do not have information on HIV treatment or outcomes of treatment for these cases. Nevertheless, most people living with HIV in England take antiretroviral therapy and have an undetectable viral load (8). §Estimated date of vaccination was available for 33 out of 52 vaccinated cases, all of whom received the Modified Vaccinia Ankara–Bavarian Nordic vaccine >2 weeks before infection. ¶Includes 1 person who reported receiving 3 doses.

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References
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Page created: August 27, 2024
Page updated: September 23, 2024
Page reviewed: September 23, 2024
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