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Volume 30, Number 10—October 2024
Dispatch
Circovirus Hepatitis in Immunocompromised Patient, Switzerland
Figure 2
![Phylogenetic analysis of the circovirus isolate from a patient with hepatitis of unknown origin, Switzerland (HCirV-1-CH). Capsid protein sequences representative of human and animal circovirus strains are shown. We aligned sequences by using MAFFT (https://mafft.cbrc.jp/alignment/software) under the L-INS-I parameter and performed maximum-likelihood phylogenetic reconstruction through the IQ-Tree portal (http://www.iqtree.org). Red indicates HCirV-1-FR, HCirV-1-CH, and HuCV2 sequences. Tree scale indicates the number of amino acid substitutions per site. Display range for bootstraps is 0.5–1.0. GenBank accession numbers are provided. HCirV-1-CH, human circovirus 1 from patient in Switzerland; HCirV-1-FR, published human circovirus 1 genome from France; HuCV2, human circovirus sequence detected in injection drug users in China (10); PCV, porcine circovirus.](/eid/images/24-0678-F2.jpg)
Figure 2. Phylogenetic analysis of the circovirus isolate from a patient with hepatitis of unknown origin, Switzerland (HCirV-1-CH). Capsid protein sequences representative of human and animal circovirus strains are shown. We aligned sequences by using MAFFT (https://mafft.cbrc.jp/alignment/software) under the L-INS-I parameter and performed maximum-likelihood phylogenetic reconstruction through the IQ-Tree portal (http://www.iqtree.org). Red indicates HCirV-1-FR, HCirV-1-CH, and HuCV2 sequences. Tree scale indicates the number of amino acid substitutions per site. Display range for bootstraps is 0.5–1.0. GenBank accession numbers are provided. HCirV-1-CH, human circovirus 1 from patient in Switzerland; HCirV-1-FR, published human circovirus 1 genome from France; HuCV2, human circovirus sequence detected in injection drug users in China (10); PCV, porcine circovirus.
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1These first authors contributed equally to this article.
2These senior authors contributed equally to this article.