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Volume 30, Number 10—October 2024
Dispatch

Circovirus Hepatitis in Immunocompromised Patient, Switzerland

Baptiste Hamelin1, Philippe Pérot1, Ian Pichler1, Jasmin D. Haslbauer, David Hardy, David Hing, Sarra Loulizi, Béatrice Regnault, Anouk Pieters, Ingmar Heijnen, Caroline Berkemeier, Maria Mancuso, Verena Kufner, Niels Willi, Anne Jamet, Nolwenn Dheilly, Marc Eloit, Mike Recher, Michael Huber2, and Kirsten D. Mertz2Comments to Author 
Author affiliations: Cantonal Hospital Baselland, Liestal, Switzerland (B. Hamelin, M. Mancuso, N. Willi, K.D. Mertz); University Hospital Basel, Basel, Switzerland (B. Hamelin, J.D. Haslbauer, I. Heijnen, C. Berkemeier, M. Mancuso, N. Willi, M. Recher, K.D. Mertz); Institut Pasteur, Paris, France (P. Pérot, D. Hardy, D. Hing, S. Loulizi, B. Regnault, N. Dheilly, M. Eloit); University of Zurich, Zurich, Switzerland (I. Pichler, V. Kufner, M. Huber); University of Basel Department of Biomedicine, Basel (A. Pieters, M. Recher, K.D. Mertz); Assistance Publique–Hôpitaux de Paris Centre Université de Paris Cité Necker-Enfants Malades Hospital, Paris (A. Jamet)

Main Article

Figure 2

Phylogenetic analysis of the circovirus isolate from a patient with hepatitis of unknown origin, Switzerland (HCirV-1-CH). Capsid protein sequences representative of human and animal circovirus strains are shown. We aligned sequences by using MAFFT (https://mafft.cbrc.jp/alignment/software) under the L-INS-I parameter and performed maximum-likelihood phylogenetic reconstruction through the IQ-Tree portal (http://www.iqtree.org). Red indicates HCirV-1-FR, HCirV-1-CH, and HuCV2 sequences. Tree scale indicates the number of amino acid substitutions per site. Display range for bootstraps is 0.5–1.0. GenBank accession numbers are provided. HCirV-1-CH, human circovirus 1 from patient in Switzerland; HCirV-1-FR, published human circovirus 1 genome from France; HuCV2, human circovirus sequence detected in injection drug users in China (10); PCV, porcine circovirus.

Figure 2. Phylogenetic analysis of the circovirus isolate from a patient with hepatitis of unknown origin, Switzerland (HCirV-1-CH). Capsid protein sequences representative of human and animal circovirus strains are shown. We aligned sequences by using MAFFT (https://mafft.cbrc.jp/alignment/software) under the L-INS-I parameter and performed maximum-likelihood phylogenetic reconstruction through the IQ-Tree portal (http://www.iqtree.org). Red indicates HCirV-1-FR, HCirV-1-CH, and HuCV2 sequences. Tree scale indicates the number of amino acid substitutions per site. Display range for bootstraps is 0.5–1.0. GenBank accession numbers are provided. HCirV-1-CH, human circovirus 1 from patient in Switzerland; HCirV-1-FR, published human circovirus 1 genome from France; HuCV2, human circovirus sequence detected in injection drug users in China (10); PCV, porcine circovirus.

Main Article

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Main Article

1These first authors contributed equally to this article.

2These senior authors contributed equally to this article.

Page created: August 13, 2024
Page updated: September 23, 2024
Page reviewed: September 23, 2024
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