Circovirus Hepatitis in Immunocompromised Patient, Switzerland
Baptiste Hamelin
1, Philippe Pérot
1, Ian Pichler
1, Jasmin D. Haslbauer, David Hardy, David Hing, Sarra Loulizi, Béatrice Regnault, Anouk Pieters, Ingmar Heijnen, Caroline Berkemeier, Maria Mancuso, Verena Kufner, Niels Willi, Anne Jamet, Nolwenn Dheilly, Marc Eloit, Mike Recher, Michael Huber
2, and Kirsten D. Mertz
2
Author affiliations: Cantonal Hospital Baselland, Liestal, Switzerland (B. Hamelin, M. Mancuso, N. Willi, K.D. Mertz); University Hospital Basel, Basel, Switzerland (B. Hamelin, J.D. Haslbauer, I. Heijnen, C. Berkemeier, M. Mancuso, N. Willi, M. Recher, K.D. Mertz); Institut Pasteur, Paris, France (P. Pérot, D. Hardy, D. Hing, S. Loulizi, B. Regnault, N. Dheilly, M. Eloit); University of Zurich, Zurich, Switzerland (I. Pichler, V. Kufner, M. Huber); University of Basel Department of Biomedicine, Basel (A. Pieters, M. Recher, K.D. Mertz); Assistance Publique–Hôpitaux de Paris Centre Université de Paris Cité Necker-Enfants Malades Hospital, Paris (A. Jamet)
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Figure 1
Figure 1. Clinical course of patient with hepatitis of unknown origin, Switzerland, November 2021–April 2024. Top of timeline shows results of enzyme level testing, expressed as units per liter; bottom of timeline shows clinical course. ALP, alkaline phosphatase; ALT, alanine aminotransferase; ARDS, acute respiratory distress syndrome; AST, aspartate aminotransferase; GGT, gammaglutamyl transferase; HCirV-1, human circovirus; mNGS, metagenomic next-generation sequencing; MRCP, magnetic resonance cholangiopancreatography; PCV3, porcine circovirus 3.
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