Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 30, Number 2—February 2024
Dispatch

Residual Immunity from Smallpox Vaccination and Possible Protection from Mpox, China

Yu Huang1, Li Guo1, Yanan Li1, Lili Ren1, Jiqin Nie1, Fengwen Xu1, Tingxuan Huang, Jingchuan Zhong, Zhangling Fan, Yin Zhang, Yu Xie, Qiao Zhang, Shan Mei, Yan Xiao, Xinming Wang, Liuhui Xu, Fei Guo2Comments to Author , and Jianwei Wang2Comments to Author 
Author affiliations: NHC Key Laboratory of Systems Biology of Pathogens, National Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China (Y. Huang, L. Guo, Y. Li, L. Ren, J. Nie, F. Xu, T. Huang, J. Zhong, Z. Fan, Y. Zhang, Y. Xie, Q. Zhang, S. Mei, Y. Xiao, X. Wang, L. Xu, F. Guo, J. Wang); Key Laboratory of Respiratory Disease Pathogenomics, Chinese Academy of Medical Sciences, Beijing (L. Guo, L. Ren, J. Wang); National Institute of Pathogen Biology and Center for AIDS Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (Y. Huang, F. Xu, Z. Fan, Y. Xie, S. Mei, F. Guo); Christophe Mérieux Laboratory, National Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (L. Guo, Y. Li, L. Ren, J. Nie, T. Huang, J. Zhong, Y. Zhang, Q. Zhang, Y. Xiao, X. Wang, L. Xu, J. Wang); Key Laboratory of Pathogen Infection Prevention and Control (Ministry of Education), State Key Laboratory of Respiratory Health and Multimorbidity, National Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (L. Guo, L. Ren, F. Guo); National Key Laboratory of Immunity and Inflammation, Beijing (J. Wang)

Main Article

Table 2

Neutralizing antibody titers against vaccinia virus Tiantan strain in persons born during 1930–1979, by birth cohort, China*

Decade of birth Neutralizing antibody titers, no. (%)
<1/4 1/4 1/8 1/16 >1/32
1930–1939, n = 106 68 (64.2) 18 (17.0) 14 (13.2) 3 (2.8) 3 (2.8)
1940–1949, n = 104 69 (66.3) 12(11.5) 17 (16.3) 5 (4.8) 1 (0.96)
1950–1959, n = 76 59 (77.6) 12 (15.8) 5 (6.6) 0 (0) 0 (0)
1960–1969, n = 95 68 (71.6) 13 (13.7) 10 (10.5) 2 (2.1) 2 (2.1)
1970–1979, n = 97
 77 (79.4)
 7 (7.2)
 5 (5.2)
 5 (5.2)
 3 (3.1)
Overall, N = 478 341 (71.3) 62 (13.0) 51 (10.7) 15 (3.1) 9 (1.9)

*Participants lived in Beijing, Shanxi Province, Heilongjiang Province, Hubei Province, or Shenzhen.

Main Article

1These first authors contributed equally to this article.

2These senior authors contributed equally to this article.

Page created: November 30, 2023
Page updated: January 24, 2024
Page reviewed: January 24, 2024
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external