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Volume 30, Number 2—February 2024
Dispatch

Emerging Enterovirus A71 Subgenogroup B5 Causing Severe Hand, Foot, and Mouth Disease, Vietnam, 2023

Nguyen Van Vinh Chau, Tang Chi Thuong, Nguyen Thanh Hung, Nguyen Thi Thu Hong, Du Tuan Quy, Tran Ba Thien, Cao Minh Hiep, Ngo Ngoc Quang Minh, Truong Huu Khanh, Do Duong Kim Han, Truong Hoang Chau Truc, Nguyen Thi Han Ny, Le Kim Thanh, Lam Anh Nguyet, Cao Thu Thuy, Le Nguyen Truc Nhu, Pham Van Quang, Phung Nguyen The Nguyen, Phan Tu Qui, H. Rogier van Doorn, C. Louise Thwaites, Tran Tan Thanh, Nguyen Thanh Dung, Guy Thwaites, Nguyen To Anh, Le Nguyen Thanh Nhan, Le Van TanComments to Author , and for the SEACOVARIANTS1
Author affiliations: Department of Health, Ho Chi Minh City, Vietnam (N.V.V. Chau, T.C. Thuong); Children’s Hospital 1, Ho Chi Minh City (N.T. Hung, D.T. Quy, C.M. Hiep, N.N.Q. Minh, T.H. Khanh, P.V. Quang, P.N.T. Nguyen, L.N.T. Nhan); Oxford University Clinical Research Unit, Ho Chi Minh City (N.T.T. Hong, T.B. Thien, D.D.K. Han, T.H.C. Truc, N.T.H. Ny, L.K. Thanh, L.A. Nguyet, C.T. Thuy, L.N.T. Nhu, H.R. van Doorn, C.L. Thwaites, T.T. Thanh, G. Thwaites, N.T. Anh, L.V. Tan); Pham Ngoc Thach University of Medicine, Ho Chi Minh City (P.V. Quang); University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City (P.N.T. Nguyen); Hospital for Tropical Diseases, Ho Chi Minh City (P.T. Qui, N.T. Dung); University of Oxford, Oxford, UK (H.R. van Doorn, C.L. Thwaites, G. Thwaites, L.V. Tan)

Main Article

Table 2

Age comparisons among patient groups infected with different enterovirus subgenogroups over time in study of emerging EV-A71 subgenogroup B5 causing severe hand, foot, and mouth disease, Vietnam, 2023*

Age EV-A71
 EV-A71 B5
 EV-A71 C4†
2023 2013–2018 p value 2023 2013–2018 p value 2013–2018 p value
Median age, mo (IQR) 27 (21–36) 21 (15–31) <0.001 28 (21–36) 18 (13–30) <0.001 22 (17–33) 0.042

*Wilcoxon rank-sum test with continuity correction was applied for analyses of patient ages among groups. EV-A71, enterovirus A71; IQR, interquartile range. †Comparison was between EV-A71 subgenogroup B5 detected during 2023 vs. EV-A71 subgenogroup C4 detected during 2013–2018.

Main Article

1Members are listed at the end of this article.

Page created: December 08, 2023
Page updated: January 24, 2024
Page reviewed: January 24, 2024
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