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Volume 30, Number 3—March 2024
Synopsis

Concurrent Clade I and Clade II Monkeypox Virus Circulation, Cameroon, 1979–2022

Delia D. Djuicy, Serge A. Sadeuh-Mba1, Chanceline N. Bilounga, Martial G. Yonga, Jules B. Tchatchueng-Mbougua, Gael D. Essima, Linda Esso, Inès M.E. Nguidjol, Steve F. Metomb, Cornelius Chebo, Samuel M. Agwe, Placide A. Ankone, Firmin N.N. Ngonla, Hans M. Mossi, Alain G.M. Etoundi, Sara I. Eyangoh, Mirdad Kazanji, and Richard NjouomComments to Author 
Author affiliations: Centre Pasteur of Cameroon, Yaounde, Cameroon (D.D. Djuicy, S.A. Sadeuh-Mba, M.G. Yonga, J.B. Tchatchueng-Mbougua, G.D. Essima, S.I. Eyangoh, M. Kazanji, R. Njouom); Ministry of Public Health, Yaounde (C.N. Bilounga, L. Esso, I.M.E. Nguidjol, S.F. Metomb, C. Chebo, S.M. Agwe, P.A. Ankone, F.N.N. Ngonla, H.M. Mossi, A.G.M. Etoundi); University of Douala, Cameroon (C.N. Bilounga); University of Bamenda, Cameroon (L. Esso)

Main Article

Figure 4

Maximum-likelihood phylogenetic tree of sequences in a study of concurrent clade I and clade II monkeypox virus circulation, Cameroon, 1979–2022. The tree is based on the Hasegawa-Kishino-Yano model inferred from a 942-bp fragment of the ATI gene, including 8 virus sequences from Cameroon generated in this work (bold text) and 55 reference sequences from GenBank. The tree with the highest log likelihood (−1,340.35) is shown. To test the robustness of the tree topology, 1,000 bootstrap replicates were performed. For a better display of the tree, the size of the 2 main midpoint rooted branches (represented in gray) that support the differentiation of the 2 monkeypox virus clades have been divided by half. Mpox strains from Cameroon are closely related to clades I and II, especially clade IIb for which a highlighted link to the ongoing global mpox epidemic is noted. Scale bar indicates number of substitutions per site. CAR, Central African Republic; DRC, Democratic Republic of the Congo; USA, United States.

Figure 4. Maximum-likelihood phylogenetic tree of sequences in a study of concurrent clade I and clade II monkeypox virus circulation, Cameroon, 1979–2022. The tree is based on the Hasegawa-Kishino-Yano model inferred from a 942-bp fragment of the ATI gene, including 8 virus sequences from Cameroon generated in this work (bold text) and 55 reference sequences from GenBank. The tree with the highest log likelihood (−1,340.35) is shown. To test the robustness of the tree topology, 1,000 bootstrap replicates were performed. For a better display of the tree, the size of the 2 main midpoint rooted branches (represented in gray) that support the differentiation of the 2 monkeypox virus clades have been divided by half. Mpox strains from Cameroon are closely related to clades I and II, especially clade IIb for which a highlighted link to the ongoing global mpox epidemic is noted. Scale bar indicates number of substitutions per site. CAR, Central African Republic; DRC, Democratic Republic of the Congo; USA, United States.

Main Article

1Current affiliation: Maryland Department of Agriculture, Salisbury, Maryland, USA.

Page created: January 18, 2024
Page updated: February 22, 2024
Page reviewed: February 22, 2024
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