Volume 30, Number 4—April 2024
CME ACTIVITY - Research
Deaths Associated with Pediatric Hepatitis of Unknown Etiology, United States, October 2021–June 2023
Table 5
Patient ID | Respiratory specimen | Stool specimen | Normally sterile site (blood or joint)† | Total no. pathogens detected |
---|---|---|---|---|
1 |
Adenovirus |
Adenovirus |
Adenovirus; Streptococcus pneumoniae |
2 |
2 |
Adenovirus; respiratory syncytial virus |
Adenovirus |
2 |
|
3 |
Adenovirus; rhinovirus/enterovirus |
Adenovirus |
2 |
|
4 |
Adenovirus; rhinovirus/enterovirus |
Adenovirus |
2 |
|
5 |
Staphylococcus hominis; Corynebacterium; Moraxella non-liquefaciens‡ |
3 |
||
6 |
Respiratory syncytial virus |
Epstein-Barr virus |
2 |
|
7 |
Clostridioides difficile |
1 |
||
8 | Clostridioides difficile | 1 |
*Table includes all pathogens for which a positive result was detected; it does not include other testing performed for which there were no positive results (e.g., respiratory and/or gastrointestinal panels, other viral testing). Other infections may have been present, but testing was not performed or results were inconclusive. Most respiratory and GI specimens were tested as part of a multiplex PCR panel, but panels used by clinical laboratory varied. All testing was performed at the discretion of treating clinicians. † Bacterial pathogens were isolated on culture from a normally sterile site such as blood or joint fluid. Testing for viral pathogens was conducted using real-time PCR or quantitative real-time PCR testing, or by serologic assay to detect recent viral antibodies (e.g., IgM). ‡Staphylococcus hominis, Corynebacterium, and Moraxella non-liquefaciens may reflect contamination of specimen collection and not necessarily infection.
1These authors contributed equally to this article.
2Members of the group are listed at the end of this article.