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Volume 30, Number 4—April 2024
CME ACTIVITY - Research

Deaths Associated with Pediatric Hepatitis of Unknown Etiology, United States, October 2021–June 2023

Olivia Almendares1Comments to Author , Julia M. Baker1, David E. Sugerman, Umesh D. Parashar, Sarah Reagan-Steiner, Hannah L. Kirking, Paul A. Gastañaduy, Jacqueline E. Tate, and Hepatitis of Unknown Etiology Group2
Author affiliation: Centers for Disease Control and Prevention, Atlanta, Georgia, USA

Main Article

Figure

Health status at initial visit and timeline of clinical course for 8 children fatally ill with hepatitis of unknown etiology, United States, October 1, 2021–June 6, 2023. Symptom onset refers to the first symptom reported for the child including respiratory, gastrointestinal, hepatic, or systemic symptoms. Patients 1 and 2 were immunocompromised at the time of initial visit to emergency department or inpatient admission. Patient 3, initially immunocompetent, tested positive only after receiving a liver transplant during initial admission; before the transplant, the child had tested negative for adenovirus in respiratory, whole blood, and liver specimens. ED, emergency department.

Figure. Health status at initial visit and timeline of clinical course for 8 children fatally ill with hepatitis of unknown etiology, United States, October 1, 2021–June 6, 2023. Symptom onset refers to the first symptom reported for the child including respiratory, gastrointestinal, hepatic, or systemic symptoms. Patients 1 and 2 were immunocompromised at the time of initial visit to emergency department or inpatient admission. Patient 3, initially immunocompetent, tested positive only after receiving a liver transplant during initial admission; before the transplant, the child had tested negative for adenovirus in respiratory, whole blood, and liver specimens. ED, emergency department.

Main Article

1These authors contributed equally to this article.

2Members of the group are listed at the end of this article.

Page created: March 12, 2024
Page updated: March 19, 2024
Page reviewed: March 19, 2024
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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