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Volume 30, Number 4—April 2024
Dispatch

Isolation of Batborne Neglected Zoonotic Agent Issyk-Kul Virus, Italy

Davide LelliComments to Author , Ana Moreno, Sabrina Canziani, Laura Soliani, Maya Carrera, Anna Castelli, Francesca Faccin, Tiziana Trogu, Enrica Sozzi, Gian Luca Cavallari, Matteo Mauri, Fabiana Ferrari, Cristian Salogni, Chiara Garbarino, Chiara Chiapponi, Marco Farioli, and Antonio Lavazza
Author affiliations: University of Parma via Gramsci, Parma, Italy (D. Lelli); Istituto Zooprofilattico Sperimentale della Lombardia e dell’Emilia Romagna, Brescia, Italy (D. Lelli, A. Moreno, S. Canziani, L. Soliani, M. Carrera, A. Castelli, F. Faccin, T. Trogu, E. Sozzi, C. Salogni, C. Garbarino, C. Chiapponi, A. Lavazza); Wildlife Rehabilitation Center WWF of Valpredina, Cenate Sopra, Italy (G.L. Cavallari, M. Mauri); Piacenza Wildlife Rescue Centre, Piacenza, italy (F. Ferrari); DG Welfare Regione Lombardia, Milano, Italy (M. Farioli)

Main Article

Figure 1

Microscopic appearance of Issyk-Kul virus IT-297348-34/2022, isolated from a Hypsugo savii bat, in study of batborne neglected zoonotic agent Issyk-Kul virus, Italy. A) Issyk-Kul–infected MARC 145 cells, mock infection; original magnification ×10. B) Issyk-Kul–infected MARC 145 cells showing cytopathic effect at 120 hours after infection; original magnification ×4. C) Issyk-Kul–infected MARC 145 cells showing cytopathic effect at 120 hours after infection; original magnification ×10. D) Negative-staining electron microscopy performed on cell supernatants (NaPT 2%), showing a viral particle of 55–60 nm morphologically referable to nairovirus; original magnification ≈x550,000

Figure 1. Microscopic appearance of Issyk-Kul virus IT-297348-34/2022, isolated from a Hypsugo savii bat, in study of batborne neglected zoonotic agent Issyk-Kul virus, Italy. A) Issyk-Kul–infected MARC 145 cells, mock infection; original magnification ×10. B) Issyk-Kul–infected MARC 145 cells showing cytopathic effect at 120 hours after infection; original magnification ×4. C) Issyk-Kul–infected MARC 145 cells showing cytopathic effect at 120 hours after infection; original magnification ×10. D) Negative-staining electron microscopy performed on cell supernatants (NaPT 2%), showing a viral particle of 55–60 nm morphologically referable to nairovirus; original magnification ≈x550,000

Main Article

Page created: March 01, 2024
Page updated: March 20, 2024
Page reviewed: March 20, 2024
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