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Volume 30, Number 4—April 2024
Research Letter

Link between Monkeypox Virus Genomes from Museum Specimens and 1965 Zoo Outbreak

Michelle HämmerleComments to Author , Aigerim Rymbekova, Pere Gelabert, Susanna Sawyer, Olivia Cheronet, Paolo Bernardi, Sébastien Calvignac-Spencer, Martin Kuhlwilm1, Meriam Guellil1, and Ron Pinhasi1Comments to Author 
Author affiliations: University of Vienna, Vienna, Austria (M. Hämmerle, A. Rymbekova, P. Gelabert, S. Sawyer, O. Cheronet, P. Bernardi, M. Kuhlwilm, M. Guellil, R. Pinhasi); Helmholtz Centre for Infection Research, Greifswald, Germany (S. Calvignac-Spencer); University of Greifswald, Greifswald (S. Calvignac-Spencer)

Main Article

Table

Relevant mapping statistics of MPXV genomes from the museum orangutan specimens from Europe when mapped to the genome responsible for the MPXV zoo outbreak in Rotterdam, the Netherlands, 1965

Sample No. sequenced reads Mapped reads no. duplicates, MQ>30 Mean mapping quality Mean fragment length, bp Mean coverage depth, + SD
% Coverage
 Frequency first base
1× 5× 10× C to G G to A
MAM1965-547 3,139,078 27,482 36.39 125.6 19.12 + 10.60 98.73 96.8 81.85 0.023 0
MAM1965-545 1,492,386 12,963 36.6 135.68 9.57 + 5.11 98.56 84.73 38.83 0.024 0
MAM1965-544 151,272 67 34.35 64.36 0.03 + 0.24 1.812 0 0 0.143 0
MAM1965-546 270,634 4,616 36.28 108.89 2.81 + 2.62 78.78 21.48 1.54 0.014 0

*MPXV, monkeypox virus; MQ, mapping quality.

Main Article

1These authors contributed equally to this article.

Page created: March 01, 2024
Page updated: March 21, 2024
Page reviewed: March 21, 2024
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