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Volume 30, Number 5—May 2024
Synopsis

Crimean Congo Hemorrhagic Fever Virus for Clinicians—Virology, Pathogenesis, and Pathology

Maria G. FrankComments to Author , Gretchen Weaver, Vanessa Raabe1, and State of the Clinical Science Working Group of the National Emerging Pathogens Training and Education Center’s Special Pathogens Research Network
Author affiliations: Denver Health and Hospital Authority, Denver, Colorado, USA (M.G. Frank); University of Colorado School of Medicine, Denver (M.G. Frank); University of Massachusetts Chan Medical School, Worchester, Massachusetts, USA (G. Weaver); New York University Grossman School of Medicine, New York, New York, USA (V. Raabe)

Main Article

Figure

Flowchart showing an abbreviated proposed pathway for Crimean-Congo hemorrhagic fever virus pathogenesis. CCHFV, Crimean-Congo hemorrhagic fever virus; DC, dendritic cell; DIC, disseminated intravascular coagulation; EC, endothelial cell; IL, interleukin; LN, lymph nodes; MCP, monocyte chemoattractant protein; MO, macrophage; MOF, multiorgan failure; SAT, saliva-assisted transmission; TNF, tumor necrosis factor; VE, vascular endothelium.

Figure. Flowchart showing an abbreviated proposed pathway for Crimean-Congo hemorrhagic fever virus pathogenesis. CCHFV, Crimean-Congo hemorrhagic fever virus; DC, dendritic cell; DIC, disseminated intravascular coagulation; EC, endothelial cell; IL, interleukin; LN, lymph nodes; MCP, monocyte chemoattractant protein; MO, macrophage; MOF, multiorgan failure; SAT, saliva-assisted transmission; TNF, tumor necrosis factor; VE, vascular endothelium.

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Main Article

1Current affiliation: Pfizer Inc., New York, New York, USA. These materials reflect only the personal views of the author and may not reflect the views of her employer.

2Members of this group are listed at the end of this article.

Page created: March 28, 2024
Page updated: April 25, 2024
Page reviewed: April 25, 2024
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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