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Volume 30, Number 6—June 2024

Research

Outbreak of Highly Pathogenic Avian Influenza A(H5N1) Virus in Seals, St. Lawrence Estuary, Quebec, Canada1

Stéphane LairComments to Author , Louise Quesnel, Anthony V. Signore, Pauline Delnatte, Carissa Embury-Hyatt, Marie-Soleil Nadeau, Oliver Lung, Shannon T. Ferrell, Robert Michaud, and Yohannes Berhane
Author affiliations: Université de Montréal, St. Hyacinthe, Quebec, Canada (S. Lair, L. Quesnel, P. Delnatte, S.T. Ferrell); Canadian Food Inspection Agency, Winnipeg, Manitoba, Canada (A.V. Signore, C. Embury-Hyatt, O. Lung, Y. Berhane); Ministère de l’Agriculture, des Pêcheries et de l’Alimentation du Quebec, St. Hyacinthe (M.-S. Nadeau); Groupe de recherche et d’éducation sur les mammifères marins, Tadoussac, Quebec, Canada (R. Michaud).

Main Article

Figure 4

Detection of influenza virus antigen by immunohistochemistry in brain (A) and lung (B) of harbor seals (Phoca vitulina) infected by highly pathogenic avian influenza A(H5N1) virus, St. Lawrence Estuary, Quebec, Canada, 2022. A) Brain tissue. Multifocal areas of intense immunostaining (arrows) with staining of all structures are seen in the affected area, including neurons and neuropil (inset). Scale bar indicates 2 mm. B) Lung tissue. Positive immunostaining can be observed within alveolar septae (arrow) and in bronchiolar epithelial cells (arrowhead). Scale bar indicates 80 µm.

Figure 4. Detection of influenza virus antigen by immunohistochemistry in brain (A) and lung (B) of harbor seals (Phoca vitulina) infected by highly pathogenic avian influenza A(H5N1) virus, St. Lawrence Estuary, Quebec, Canada, 2022. A) Brain tissue. Multifocal areas of intense immunostaining (arrows) with staining of all structures are seen in the affected area, including neurons and neuropil (inset). Scale bar indicates 2 mm. B) Lung tissue. Positive immunostaining can be observed within alveolar septae (arrow) and in bronchiolar epithelial cells (arrowhead). Scale bar indicates 80 µm.

Main Article

1Preliminary results from this study were presented at the International Association for Aquatic Animal Medicine Conference, May 24, 2023, Salt Lake City, Utah, USA.

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Page updated: May 22, 2024
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