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Volume 30, Number 6—June 2024
Research

Estimates of SARS-CoV-2 Hospitalization and Fatality Rates in the Prevaccination Period, United States

Isabel GriffinComments to Author , Jessica King1, B. Casey Lyons1, Alyson L. Singleton1, Xidong Deng, Beau B. Bruce, and Patricia M. Griffin
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (I. Griffin, J. King, B.C. Lyons, X. Deng, B.B. Bruce, P.M. Griffin); Oak Ridge Institute for Science and Education, Oak Ridge, Tennessee, USA (A.L. Singleton)

Main Article

Table 1

Demographic and clinical characteristics of SARS-CoV-2 infections that met inclusion criteria for case hospitalization rate analysis, United States, 2020*

Characteristic Includes cases for which hospitalization status was unknown, counted as not hospitalized
 Includes only cases for which hospitalization status was known
No. hospitalizations No. cases Case-hospitalization rate, % No. hospitalizations No. cases Case-hospitalization rate, %
Overall
 140,644
 2,479,423
 5.7
140,644
 1,791,896
 7.9
Sex
M 72,372 1,164,257 6.2 72,372 834,733 8.7
F 67,894 1,300,788 5.2 67,894 946,921 7.2
Other 2 18 11.1 2 12 16.7
Missing† 134 4,006 3.3 134 2,657 5.0
Unknown
 242
 10,354
 2.3
242
 7,573
 3.2
Age group, y
<1 564 11,208 5.0 564 8,478 6.7
1–4 386 32,180 1.2 386 24,791 1.6
5–14 823 137,646 0.6 823 104,483 0.8
15–24 4,228 470,395 0.9 4,228 337,187 1.3
25–34 8,035 429,855 1.9 8,035 305,416 2.6
35–44 10,391 373,602 2.8 10,391 270,249 3.8
45–54 16,723 357,683 4.7 16,723 257,484 6.5
55–64 25,361 309,488 8.2 25,361 221,684 11.4
65–74 31,181 190,946 16.3 31,181 141,469 22.0
75–84 26,967 103,990 25.9 26,967 77,281 34.9
>85 15,973 61,604 25.9 15,973 42,872 37.3
Missing†
 12
 826
 1.5
12
 502
 2.4
Race and ethnicity†§
AI or AN, NH 1,974 26,745 7.4 1,974 21,821 9.1
Asian or PI, NH 3,468 49,774 7.0 3,468 43,118 8.0
AA or Black, NH 18,470 161,642 11.4 18,470 133,485 13.8
Hispanic 17,159 365,476 4.7 17,159 304,239 5.6
Other or multiple races, NH 4,705 60,408 7.8 4,705 47,583 9.9
White, NH 69,165 1,068,295 6.5 69,165 870,193 8.0
Unknown
 25,703
 747,083
 3.4
25,703
 371,457
 6.9
Symptom status
Symptomatic 105,131 1,664,240 6.3 105,131 1,484,676 7.1
Asymptomatic 1,870 55,987 3.3 1,870 50,657 3.7
Missing† 11,423 168,365 6.8 11,423 82,936 13.8
Unknown 22,220 590,831 3.8 22,220 173,627 12.8

*Data from 21 jurisdictions that met the study inclusion criteria, Case Only Epi Task Force dataset, accessed March 17, 2021, based on responses to the CDC 2019 Novel Coronavirus Case Report Form during May 1–December 1, 2020 (Figure). Reports in which no response was provided about hospitalization were excluded from the rate calculation. AA, African American; AI, American Indian; AN, Alaska Native; NH, not Hispanic or Latino; PI, Pacific Islander. †Missing indicates that the field was left blank. ‡Other or multiple races category includes NH persons whose race was reported as other or for whom >1 race was reported and persons whose record had both a racial designation and “racial information unknown” selected. The unknown category includes cases who have a known ethnicity of NH but either unknown or missing race; have a known race but either unknown or missing ethnicity; or have both unknown or missing race and unknown or missing ethnicity. §The jurisdictions used for the hospitalization calculation had a smaller percentage of AA or Black, NH; Asian or PI, NH; and Hispanic persons, and a larger percentage of White, NH; and AI or AN, NH, persons than the US 2019 population.

Main Article

1These authors contributed equally to this article.

Page created: May 02, 2024
Page updated: May 22, 2024
Page reviewed: May 22, 2024
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