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Volume 30, Number 7—July 2024
Research

Newly Recognized Spotted Fever Group Rickettsia as Cause of Severe Rocky Mountain Spotted Fever–Like Illness, Northern California, USA

Will S. ProbertComments to Author , Monica P. Haw, Aran C. Nichol, Carol A. Glaser, Sarah Y. Park, Laura E. Campbell, Kavita K. Trivedi, Hannah Romo, Megan E.M. Saunders, Anne M. Kjemtrup, Kerry A. Padgett, and Jill K. Hacker
Author affiliations: California Department of Public Health, Richmond, California, USA (W.S. Probert, M.P. Haw, C.A. Glaser, H. Romo, M.E.M Saunders, K.A. Padgett, J.K. Hacker); Kaiser Permanente, Oakland, California, USA (A.C. Nichol); Karius, Redwood City, California, USA (S.Y. Park); Alameda County Public Health Department, San Leandro, California, USA (L.E. Campbell, K.K. Trivedi); California Department of Public Health, Sacramento, California, USA (A.M. Kjemtrup)

Main Article

Table 2

Comparison of real-time PCR results for case-patient 1 and retrospective SFG rickettsiosis case-patients in study of newly recognized SFG Rickettsia as cause of severe RMSF-like illness, northern California, USA*

SFG rickettsiosis case-patient Specimen type Cycle threshold value, by test type
Triplex Rickettsia spp. Triplex R. rickettsii SNP Triplex R. typhi SNP RRi6 R. rickettsii Rickettsia sp. CA6269 ompA
1 Plasma 24.9 ND ND 30.5 29.6
2 Serum 34.3 ND ND 34.3 34.4
3 Plasma 23.3 25.2 ND 25.4 ND
4 Serum 30.3 27 ND 34 ND
5 Serum 32.8 30.2 ND 35 ND
6 Serum 32.2 32.8 ND 33.6 ND
7 Plasma 29.5 29.2 ND 33.3 ND
8 Serum 20.8 19.2 ND 25.1 ND
9 Plasma 28.6 27.3 ND 30.2 ND

*ND, not detected; RMSF, Rocky Mountain spotted fever; SFG, spotted fever group; SNP, single-nucleotide polymorphism.

Main Article

Page created: May 17, 2024
Page updated: June 22, 2024
Page reviewed: June 22, 2024
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