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Volume 30, Number 9—September 2024

Research

Role of Direct Sexual Contact in Human Transmission of Monkeypox Virus, Italy

Giuseppe Sberna, Gabriella Rozera, Claudia Minosse, Licia BordiComments to Author , Valentina Mazzotta, Alessandra D’Abramo, Enrico Girardi, Andrea Antinori, Fabrizio Maggi, and Eleonora Lalle
Author affiliation: National Institute for Infectious Diseases, Lazzaro Spallanzani, Rome, Italy

Main Article

Figure 1

In vitro kinetics of MPXV infection in Vero E6 cell line in study of role of direct sexual contact in human transmission of MPXV, Italy. Cell-associated G2R-mRNA, a surrogate marker of ongoing replication, was detected at low levels until 30 minutes postinfection, when it started to increase, showing a peak at 1 hour postinfection. After 1 hour, a slight increase was observed until 24 hours; levels remained stable thereafter. MPXV DNA levels released in the supernatant steadily increased at each time point, peaking at 24 hours postinfection. MPXV, monkeypox virus.

Figure 1. In vitro kinetics of MPXV infection in Vero E6 cell line in study of role of direct sexual contact in human transmission of MPXV, Italy. Cell-associated G2R-mRNA, a surrogate marker of ongoing replication, was detected at low levels until 30 minutes postinfection, when it started to increase, showing a peak at 1 hour postinfection. After 1 hour, a slight increase was observed until 24 hours; levels remained stable thereafter. MPXV DNA levels released in the supernatant steadily increased at each time point, peaking at 24 hours postinfection. MPXV, monkeypox virus.

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Page created: July 19, 2024
Page updated: August 21, 2024
Page reviewed: August 21, 2024
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