Volume 30, Number 9—September 2024
Research
Role of Direct Sexual Contact in Human Transmission of Monkeypox Virus, Italy
Giuseppe Sberna, Gabriella Rozera, Claudia Minosse, Licia Bordi
, Valentina Mazzotta, Alessandra D’Abramo, Enrico Girardi, Andrea Antinori, Fabrizio Maggi, and Eleonora Lalle
, Valentina Mazzotta, Alessandra D’Abramo, Enrico Girardi, Andrea Antinori, Fabrizio Maggi, and Eleonora Lalle
Table
Molecular results of analyzed samples in study of role of direct sexual contact in human transmission of MPXV, Italy*
| Sample type | Patient no. | MPXV DNA Ct | MPXV DNA ddPCR, copies/μL | G2R-mRNA ddPCR, copies/μL |
|---|---|---|---|---|
| Semen |
1 | 24.5 | 3,576 | ND |
| 2 | 34.5 | 2.2 | 2.4 | |
| 4 | ND | NT | NT | |
| 5 | ND | NT | NT | |
| 6 | 27.9 | 145.2 | ND | |
| 8 | 28.7 | 98.8 | ND | |
| 11 | 34.3 | 12.4 | 6.0 | |
| 12 |
37.7 |
ND |
ND |
|
| Skin lesion swab | ||||
| Penis | 1 | 22.2 | 1,216 | 7.2 |
| Cutaneous | 2 | 13.2 | 4,000,000 | 504 |
| Penis | 3 | 24.3 | 4,296 | 3.6 |
| Scapula | 5 | 35.4 | 2.1 | 2.8 |
| Anal | 9 | 35.6 | 1,552 | 4.8 |
| Cutaneous | 10 | 15.5 | 380,000 | 608 |
| Anal | 10 | 20.0 | 49,060 | 79.6 |
| Pubis | 13 | 15.9 | 521,000 | 16.4 |
| Neck | 13 | 17.7 | 117,600 | 10.8 |
| Back |
15 |
23.0 |
8,188 |
4.4 |
| Nasopharyngeal swab |
1 | 21.2 | 22,080 | 13.2 |
| 2 | 31.1 | 48 | 1.2 | |
| 4 | 27.8 | 520 | 1.6 | |
| 5 | 37.5 | 4.9 | ND | |
| 6 | 28.5 | 164.4 | 10 | |
| 7 | 37.2 | 1.0 | ND | |
| 14 |
33.3 |
6.9 |
ND |
|
| Urine | 1 | ND | NT | NT |
| 2 | ND | NT | NT | |
| 5 | ND | NT | NT | |
| 6 | ND | NT | NT |
*Ct, cycle threshold; ddPCR, digital droplet PCR; MPXV, monkeypox virus; ND, not detected; NT, not tested.
Page created: July 19, 2024
Page updated: August 21, 2024
Page reviewed: August 21, 2024
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