Volume 30, Number 9—September 2024
CME ACTIVITY - Research
Mortality Rate and Cause of Death in Adults with Extrapulmonary Nontuberculous Mycobacteria Infection, Denmark
Andreas A. Pedersen
, Victor N. Dahl, Anders Løkke, Inge K. Holden, Andreas Fløe, Rikke Ibsen, Ole Hilberg, and Isik S. Johansen
, Victor N. Dahl, Anders Løkke, Inge K. Holden, Andreas Fløe, Rikke Ibsen, Ole Hilberg, and Isik S. Johansen
Table 4
Numbers and percentages of comorbidities 3 years before diagnosis in study of mortality and cause of death in adults with extrapulmonary NTM infection, Denmark*
| Comorbidity | Patients with extrapulmonary NTM |
Controls |
|||
|---|---|---|---|---|---|
| No. | % (95% CI) | No. | % (95% CI) | ||
| Cardiovascular disease | 188† | 38.8 (34.4–43.3) | 373 | 19.3 (17.6–21.2) | |
| Head and musculoskeletal injuries | 142† | 29.3 (25.3–33.6) | 330 | 17.1 (15.4–18.8) | |
| Other bacterial diseases including pneumonia‡ | 103† | 21.2 (17.7–25.2) | 57 | 2.9 (2.2–3.8) | |
| Urinary system diseases and symptoms | 102† | 21.0 (17.5–24.9) | 109 | 5.6 (4.6–6.8) | |
| Gastrointestinal system diseases and symptoms | 85† | 17.5 (14.2–21.2) | 122 | 6.3 (5.3–7.5) | |
| Skin and soft tissue diseases | 83† | 17.1 (13.9–20.8) | 82 | 4.2 (3.4–5.2) | |
| Arthrosis and inflammatory polyarthropathies | 59† | 12.2 (9.4–15.4) | 71 | 3.7 (2.9–4.6) | |
| Metabolic disorders | 51† | 10.5 (7.9–13.6) | 65 | 3.4 (2.6–4.3) | |
| Infections of the skin and subcutaneous tissue | 48† | 9.9 (7.4–12.9) | |||
| Diabetes mellitus | 46† | 9.5 (7.0–12.5) | 67 | 3.5 (2.7–4.4) | |
| Benign neoplasms | 42† | 8.7 (6.3–11.5) | 55 | 2.8 (2.1–3.7) | |
| Complications of surgical and medical care | 38† | 7.8 (5.6–10.6) | 49 | 2.5 (1.9–3.3) | |
| Circulatory and respiratory symptoms | 37† | 7.6 (5.4–10.4) | 67 | 3.5 (2.7–4.4) | |
| Diseases of veins, lymphatic vessels, and lymph nodes | 31† | 6.4 (4.4–9.0) | |||
| Anemia | 30† | 6.2 (4.2–8.7) | NA | NA | |
| Chronic lower respiratory diseases | 30† | 6.2 (4.2–8.7) | 49 | 2.5 (1.9–3.3) | |
| Other disorders of the ear | 28§ | 5.8 (3.9–8.2) | 89 | 4.6 (3.7–5.6) | |
| Male genital organ diseases | 28† | 5.8 (3.9–8.2) | 49 | 2.5 (1.9–3.3) | |
| HIV | 19† | 3.9 (2.4–6.1) | 4 | 0.2 (0.06−0.52) | |
| Hematological malignancies | 12¶ | 2.5 (1.3–4.3) | 18 | 0.9 (0.6–1.5) | |
*NA, not available; NTM, nontuberculosis mycobacteria. †p<0.001. ‡Codes A30–A49 (excluding A31) in International Classification of Diseases, 8th Revision or 10th Revision. §Not significant. ¶p<0.01.
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