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Volume 30, Number 9—September 2024
Dispatch

Retrospective Seroprevalence of Orthopoxvirus Antibodies among Key Populations, Kenya

Kristi Loeb1, Kieran A. Milner1, Candice Lemaille, Brielle Martens, Derek Stein, Julie Lajoie, Souradet Y. Shaw, Anne W. Rimoin, Placide Mbala-Kingebeni, Nicole A. Hoff, Ryan S. Noyce, Keith R. Fowke, Joshua Kimani, Lyle McKinnon, and Jason KindrachukComments to Author 
Author affiliations: University of Manitoba, Winnipeg, Manitoba, Canada (K. Loeb, K.A. Milner, C. Lemaille, B. Martens, D. Stein, J. Lajoie, S.Y. Shaw, K.R. Fowke, J. Kimani, L. McKinnon, J. Kindrachuk); Cadham Provincial Laboratory, Winnipeg (D. Stein); University of Nairobi, Nairobi, Kenya (J. Lajoie, K.R. Fowke, J. Kimani, L. McKinnon); University of California–Los Angeles, Los Angeles, California, USA (N.A. Hoff, A.W. Rimoin); Institut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo (P. Mbala-Kingebeni); University of Alberta, Edmonton, Alberta, Canada (R.S. Noyce)

Main Article

Figure

Retrospective assessment of orthopoxvirus antibody seropositivity among key populations, Nairobi, Kenya, 2013–2018. Orthopoxvirus seropositivity was assessed in banked samples acquired from 792 sex workers. A) Seropositivity was determined by ELISA using UV-inactivated vaccinia virus. Cutoff line indicates baseline seropositivity. Positives were determined as 3 SDs above the cutoff. Horizontal bar indicates median. B) Age distribution across all seropositive and seronegative samples. Horizontal bars indicate median with upper quartile above, lower quartile below. OD450, optical density at 450 nm.

Figure. Retrospective assessment of orthopoxvirus antibody seropositivity among key populations, Nairobi, Kenya, 2013–2018. Orthopoxvirus seropositivity was assessed in banked samples acquired from 792 sex workers. A) Seropositivity was determined by ELISA using UV-inactivated vaccinia virus. Cutoff line indicates baseline seropositivity. Positives were determined as 3 SDs above the cutoff. Horizontal bar indicates median. B) Age distribution across all seropositive and seronegative samples. Horizontal bars indicate median with upper quartile above, lower quartile below. OD450, optical density at 450 nm.

Main Article

1These first authors contributed equally to this article.

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