Emergence of Extensively Drug-Resistant Neisseria gonorrhoeae, France, 2023
François Caméléna, Manel Mérimèche, Julie Brousseau, Mary Mainardis, Pascale Verger, Caroll Le Risbé, Elise Brottet, Alexandra Thabuis, Cécile Bébéar, Jean-Michel Molina, Florence Lot, Emilie Chazelle
1, and Béatrice Berçot
1
Author affiliations: Saint Louis–Lariboisière University Hospitals, Paris, France (F. Caméléna, M. Mérimèche, J. Brousseau, M. Mainardis, J.-M. Molina, B. Berçot); French National Reference Center for bacterial STI, Paris (F. Caméléna, M. Mérimèche, J. Brousseau, M. Mainardis, B. Berçot); Paris Cité University, Paris (F. Caméléna, M. Mérimèche, J. Brousseau, J.-M. Molina, B. Berçot); Biogroup Oriade Noviale, Saint Martin d'Hères, France (P. Verger, C. Le Risbé); National Public Health Agency, Lyon, France (E. Brottet, A. Thabuis); National Reference Centre for Bacterial Sexually Transmitted Infections, Bordeaux, France (C. Bébéar); University Bordeaux, Bordeaux (C. Bébéar); Santé publique France, Saint-Maurice, France (F. Lot, E. Chazelle).
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Figure
Figure. Phylogenetic tree of 19 Neisseria gonorrhoeae isolates, including 2 from patients in France, compared on the basis of their main resistance determinants. The phylogenetic tree was built from 10,907 total core single-nucleotide polymorphism positions. The F95 and F96 isolates from 2 patients in France were compared with ceftriaxone-resistant and extensively drug-resistant N. gonorrhoeae isolates from Europe, Australia, Cambodia, Japan, and the United States. The tree is rooted on N. gonorrheae FA1090, a laboratory reference strain. Scale bar indicates the branch length corresponding to genetic change.
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