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Volume 31, Supplement—May 2025
SUPPLEMENT ISSUE
Supplement

Nationwide Implementation of HIV Molecular Cluster Detection by Centers for Disease Control and Prevention and State and Local Health Departments, United States

Anne Marie France1Comments to Author , Camden J. Hallmark1, Nivedha Panneer, Rachael Billock, Olivia O. Russell, Mary Plaster, Jessica Alberti, Fathima Nuthan, Neeraja Saduvala, David Philpott, M. Cheryl Bañez Ocfemia, Scott Cope, Angela L. Hernandez, Sergei L. Kosakovsky Pond, Joel O. Wertheim, Steven Weaver, Saja Khader, Kevin Johnson, and Alexandra M. Oster
Author affiliation: US Public Health Service Commissioned Corps, Atlanta, Georgia, USA (A.M. France, A.M. Oster); Centers for Disease Control and Prevention, Atlanta (A.M. France, C.J. Hallmark, N. Panneer, R. Billock, O.O. Russell, D. Philpott, M.C.B. Ocfemia, S. Cope, A.L. Hernandez, A.M. Oster); DLH Corporation, Atlanta (M. Plaster, J. Alberti, F. Nuthan, S. Khader); SeKON Enterprise Inc., Atlanta (N. Saduvala); Temple University, Philadelphia, Pennsylvania, USA (S.L. Kosakovsky Pond, S. Weaver); University of California San Diego, La Jolla, California, USA (J.O. Wertheim, S. Weaver); Oak Ridge Institute for Science and Education, Oak Ridge, Tennessee, USA (K. Johnson)

Main Article

Table 1

Comparison of HIV cluster detection by CDC and state and local health departments, United States*

Comparisons CDC State/local
Interval
 Quarterly
 At least monthly
Data
 National, deduplicated
 State or local
Ability to detect multijurisdictional clusters
 Yes
 Not at the time of writing
Analytic tool
 Local installation of HIV-TRACE
 Secure HIV-TRACE
Identifiable information
 No personal identifiers
 Linked to personal identifiers†
Initial notification to health departments
 CDC securely transmits notification of priority clusters to state/local health departments
 Secure HIV-TRACE automatically flags priority clusters identified in each analysis
Reporting from health departments to CDC Response activities reported to CDC via cluster report forms Response activities reported to CDC via cluster report forms

*CDC, Centers for Disease Control and Prevention; HIV-TRACE, HIV TRAnsmission Cluster Engine. †Identifiers are not uploaded to Secure HIV-TRACE or transmitted to CDC.

Main Article

1These first authors contributed equally to this article.

Page created: April 08, 2025
Page updated: May 06, 2025
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