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Two Human Cases of Fatal Meningoencephalitis Associated with Potosi and Lone Star Virus Infections, United States, 2020–2023
Charles Y. Chiu
, Raja Rama Godasi, Holly R. Hughes, Venice Servellita, Kafaya Foresythe, Asritha Tubati, Kelsey Zorn, Sukhman Sidhu, Michael R. Wilson, Sai Varun Bethina, Daniel Abenroth, Yee Cheng, Raymond Grams, Camilla Reese, Carlos Isada, and Neeharika Thottempudi
Author affiliation: Chan–Zuckerberg Biohub, San Francisco, California, USA (C.Y. Chiu); Abbott Pandemic Defense Coalition, Abbott Park, Illinois, USA (C.Y. Chiu, V. Servellita, K. Foresythe); University of California, San Francisco (C.Y. Chiu, V. Servellita, K. Foresythe, A. Tubati, K. Zorn, S. Sidhu, M.R. Wilson); St. Luke’s Boise Medical Center, Boise, Idaho, USA (R. Rama Godasi, D. Abenroth, Y. Cheng, R. Grams, C. Reese); Centers for Disease Control and Prevention, Fort Collins, Colorado, USA (H.R. Hughes); Wake Forest Baptist Medical Center, Winston-Salem, North Carolina, USA (S. Varun Bethina); Cleveland Clinic, Cleveland, Ohio, USA (C. Isada); University of Nevada, Reno, Nevada (N. Thottempudi)
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Figure
Figure. Brain magnetic resonance imaging scans from 2 patients with bunyavirus-associated meningoencephalitis, United States, 2020–2023. A, B) Case-patient 1 brain T1 postcontrast images of coronal (A) and axial (B) sections showing moderately enlarged ventricles and cerebral atrophy. C, D) Case-patient 2 brain T1 postcontrast (C) and T2 postcontrast fluid attenuated inversion recovery (D) images demonstrating bilateral basal ganglia hyperintensities with no contrast enhancement.
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