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Volume 31, Number 2—February 2025
Research

Epidemiologic and Genomic Surveillance of Vibrio cholerae and Effectiveness of Single-Dose Oral Cholera Vaccine, Democratic Republic of the Congo

Christine Marie George1Comments to Author , Alves Namunesha1, Kelly Endres, Willy Felicien, Presence Sanvura, Jean-Claude Bisimwa, Jamie Perin, Justin Bengehya, Jean Claude Kulondwa, Ghislain Maheshe, Cirhuza Cikomola, Lucien Bisimwa, Alain Mwishingo, David A. Sack, and Daryl Domman
Author affiliation: Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA (C.M. George, K. Endres, J. Perin, D.A. Sack); Université Catholique de Bukavu, Bukavu, Democratic Republic of the Congo (A. Namunesha, W. Felicien, P. Sanvura, J.-C. Bisimwa, G. Maheshe, C. Cikomola, L. Bisimwa, A. Mwishingo); Ministère de la Santé, Bukavu (J. Bengehya, J.-C. Kulondwa); University of New Mexico Health Sciences Center, Albuquerque, New Mexico, USA (D. Domman)

Main Article

Figure 2

Phylogenetic analysis of Vibrio cholerae seventh pandemic El Tor (7PET) isolates collected during study of V. cholerae transmission and effectiveness of single-dose oral cholera vaccine, Democratic Republic of the Congo. A) Maximum-likelihood tree of 255 7PET V. cholerae genomes sampled in Bukavu during 2020–2023. Node colors indicate sample type. Associated colored metadata indicate sampling year and inferred serotypes according to genome analysis. Scale bar indicates nucleotide substitutions per site. B) Minimum spanning tree of 255 7PET V. cholerae genomes sampled in Bukavu during 2020–2023. Node colors indicate sample type. Isolates with 0 single-nucleotide polymorphism differences between each other are collapsed into single node. Node sizes are scaled according to the number of samples. Scale bar indicates single-nucleotide polymorphisms.

Figure 2. Phylogenetic analysis of Vibrio cholerae seventh pandemic El Tor (7PET) isolates collected during study of V. cholerae transmission and effectiveness of single-dose oral cholera vaccine, Democratic Republic of the Congo. A) Maximum-likelihood tree of 255 7PET V. cholerae genomes sampled in Bukavu during 2020–2023. Node colors indicate sample type. Associated colored metadata indicate sampling year and inferred serotypes according to genome analysis. Scale bar indicates nucleotide substitutions per site. B) Minimum spanning tree of 255 7PET V. cholerae genomes sampled in Bukavu during 2020–2023. Node colors indicate sample type. Isolates with 0 single-nucleotide polymorphism differences between each other are collapsed into single node. Node sizes are scaled according to the number of samples. Scale bar indicates single-nucleotide polymorphisms.

Main Article

1These first authors contributed equally to this article.

Page created: December 30, 2024
Page updated: January 31, 2025
Page reviewed: January 31, 2025
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