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Volume 31, Number 3—March 2025
Dispatch

Macrolide-Resistant Mycoplasma pneumoniae Infections among Children after COVID-19 Pandemic, Ohio, USA

Amy L. Leber, Tori Embry, Kathy Everhart, Jeanette Taveras, Sophonie J. Oyeniran, and Huanyu WangComments to Author 
Author affiliation: Author affiliations: Nationwide Children’s Hospital, Columbus, Ohio, USA (A.L. Leber, T. Embry, K. Everhart, J. Taveras, S.J. Oyeniran, H. Wang); The Ohio State University, Columbus (A.L. Leber, J. Taveras, S.J. Oyeniran, H. Wang)

Main Article

Table 2

Laboratory characteristics for macrolide-resistant Mycoplasma pneumoniae infections among children after COVID-19 pandemic, by age group, Ohio, USA*

Characteristics Total no. Age group, y
p value
<2 2 to <6 6 to <10 >10
No. samples tested 18,035 5,288 4,373 3,401 4,973 NA
M. pneumoniae­–positive 2,616 (14.5) 109 (2.1) 601 (13.7) 904 (26.6) 1,002 (20.1) <0.0001
Sequenced NA 30 (27.5) 224 (37.3) 363 (40.2) 378 (37.7) NA
Macrolide-resistant
NA
1 (3.3)
6 (2.7)
12 (3.3)
6 (1.6)
NS
No. positive unique patients 2,469 82 572 865 950 NA
Sex
M 1,317 (53.3) 48 (58.5) 319 (55.8) 457 (52.8) 493 (51.9) NS
F
1,152 (46.7)
34 (41.4)
253 (44.2)
408 (47.2)
457 (48.1)

No. medical encounters 2,478 83 575 866 954 NA
Hospitalization 304 (12.3) 23 (27.7) 91 (15.8) 81 (9.4) 109 (11.4) <0.0001
Intensive care unit admission 53 (2.1) 6 (7.2) 19 (3.3) 14 (1.6) 14 (1.5) 0.0009
RP2.1 tested 359 31 98 100 130 NA
Codetection† 129 (35.9) 19 (61.3) 51 (52.0) 31 (31.0) 28 (21.5) <0.0001

*Values are no. (%) except as indicated. NA, not applicable; NS, not statistically significant; RP2.1, FilmArray Respiratory Panel version 2.1 (BioFire Diagnostics, https://www.biofiredx.com). †Codetection of M. pneumoniae and other viruses.

Main Article

Page created: January 15, 2025
Page updated: February 21, 2025
Page reviewed: February 21, 2025
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