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Volume 31, Number 3—March 2025

Dispatch

National Active Case-Finding Program for Tuberculosis in Prisons, Peru, 2024

Esther JungComments to Author , Valentina A. Alarcón, Wilfredo Santos Solís Tupes, Tatiana Avalos-Cruz, Marco Tovar, Erika Abregu, Max Z. Yang, Jason R. Andrews1, and Moises A. Huaman1
Author affiliation: Stanford University School of Medicine, Stanford, California, USA (E. Jung, M.Z. Yang, J.R. Andrews); Dirección de Prevención y Control de Tuberculosis (DPCTB), Ministerio de Salud, Lima, Peru (V.A. Alarcón, W.S. Solís Tupes, T. Avalos-Cruz, E. Abregu); Instituto de Investigación Nutricional, Lima (M. Tovar); Escuela de Medicina, Universidad Peruana de Ciencias Aplicadas, Lima (M. Tovar); University of Cincinnati College of Medicine, Cincinnati, Ohio, USA (M.A. Huaman)

Main Article

Table 2

Predictive value of CAD4TB, symptom screening, and sputum testing among participants in a national active case-finding program for TB in prisons, Peru, 2024*

CAD4TB score Symptoms No. (%) Sputum collected TB confirmed
No. confirmed % TB cases (95% CI)† % Sputum positivity (95% CI)‡
<40
N 30,335 (78.3) 333 17 1.6 (0.9–2.5) 5.1 (3.0–8.1)
Y
 2,491 (6.4)
 1,250
 85
 7.8 (6.3–9.6)
 6.8 (5.5–8.3)
≥40
N 3,786 (9.8) 3,642 445 40.9 (37.9–43.9) 12.2 (11.2–13.3)
Y
 2,122 (5.5)
 2,066
 542
 49.8 (46.8–52.8)
 26.2 (24.4–28.2)
Total 38,734 7,291 1,089

*CAD4TB, Computer-Aided Detection for Tuberculosis version 7.0 (Delft Imaging Systems, https://delft.care); TB, tuberculosis. †TB case defined as any positive or trace result via Xpert MTB/RIF Ultra (Cepheid, https://www.cepheid). ‡Sputum positivity calculated as percentage of individuals with sputum collected who are confirmed to have TB via Xpert MTB/RIF Ultra (Cepheid).

Main Article

1These senior authors contributed equally to this article.

Page created: February 04, 2025
Page updated: February 28, 2025
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