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Volume 31, Number 4—April 2025
Synopsis

Maternal and Fetal Implications of Oropouche Fever, Espírito Santo State, Brazil, 2024

João Paulo Cola1, Ana Paula Brioschi dos Santos1, Raphael Lubiana Zanotti, Adriana Endlich da Silva Dela Costa, Karina Bertazo Del Carro, Lesliane de Amorim Lacerda Coelho, Angelica Espinosa Miranda2, and Creuza Rachel Vicente2Comments to Author 
Author affiliation: Secretaria de Estado da Saúde do Espírito Santo, Vitória, Brazil (J.P. Cola, A.P. Brioschi dos Santos, R. Lubiana Zanotti, A. Endlich da Silva Dela Costa, K. Bertazo Del Carro, L. de Amorim Lacerda Coelho); Universidade Federal do Espírito Santo, Programa de Pós-Graduação em Doenças Infecciosas, Vitória (A.E. Miranda, C.R. Vicente)

Main Article

Table 2

Description of Oropouche virus infections in 15 concluded pregnancies, Espírito Santo State, Brazil, March 28–December 22, 2024*

Case Clinical manifestations in pregnant woman Weeks of gestation at diagnosis RT-PCR of pregnant woman RT-PCR of placenta Clinical manifestations in neonates RT-PCR in neonate Outcomes
1
 Fever, headache, myalgia, back pain, retro-ocular pain, nausea, and arthralgia
 7
 Positive
 NA
 NA
 NA
 Spontaneous abortion at 8 weeks of pregnancy
2
 Fever, myalgia, headache, nausea, retro-ocular pain
 7
 NA
 NA
 Asymptomatic
 Positive
 Dysgenesis of the corpus callosum
3
 Fever, headache, myalgia
 33
 Positive
 Negative
 Asymptomatic
 Negative
 No alterations
4
 Rash
 33
 Positive
 Negative
 Asymptomatic
 Negative
 No alterations
5
 Headache, myalgia
 33
 Positive
 Negative
 Asymptomatic
 NA
 No alterations
6
 Fever, headache, myalgia, nausea
 34
 Positive
 Positive
 Asymptomatic
 Negative
 No alterations
7
 Fever, headache, myalgia, nausea
 35
 Positive
 Positive
 Asymptomatic
 Negative
 No alterations
8
 Fever, headache, myalgia, back pain
 37
 Positive
 Positive
 Asymptomatic
 Negative
 No alterations
9
 Fever, headache, myalgia, back pain and rash
 37
 Positive
 Negative
 Asymptomatic
 NA
 No alterations
10
 Fever, headache, myalgia
 38
 NA
 NA
 Fever, exanthema, and agitation at 4 d of age
 Positive
 Possible intrapartum transmission
11
 Fever, headache, myalgia, and arthralgia
 38
 Positive
 Negative
 Asymptomatic
 Negative
 Hyperthermia at birth
12
 Fever, headache, myalgia, back pain
 39
 Positive
 Positive
 Asymptomatic
 Negative
 No alterations
13
 Fever, headache, myalgia, retro-ocular pain, nausea,
 40
 Positive
 Positive
 Asymptomatic
 Negative
 No alterations
14
 Fever, headache, myalgia, back pain and arthralgia
 40
 Positive
 Negative
 Asymptomatic
 NA
 No alterations
15 Fever, headache, myalgia, retro-ocular pain, nausea 40 Positive Negative Asymptomatic Negative No alterations

*Physical examinations were performed in all cases. Data on brain imaging was not available except for case 2. NA, not applicable, RT-PCR, reverse transcription PCR.

Main Article

1These first authors contributed equally to this article.

2These senior authors contributed equally to this article.

Page created: February 05, 2025
Page updated: March 24, 2025
Page reviewed: March 24, 2025
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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