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Volume 31, Number 5—May 2025
Synopsis

Comprehensive Survival Analysis of Alveolar Echinococcosis Patients, University Hospital Zurich, Zurich, Switzerland, 1973–2022

Ansgar Deibel1Comments to Author , Yanick Kindler1, Rubens Mita, Soleen Ghafoor, Cordula Meyer zu Schwabedissen, Barbara Brunner-Geissmann, Alexander Schweiger, Felix Grimm, Michael Reinehr, Achim Weber, Cäcilia S. Reiner, Andreas E. Kremer, Henrik Petrowsky, Pierre-Alain Clavien, Peter Deplazes, Stefanie von Felten, and Beat Müllhaupt
Author affiliation: University Hospital Zurich, Zurich, Switzerland (A. Deibel, Y. Kindler, S. Ghafoor, C. Meyer zu Schwabedissen, B. Brunner-Geissmann, M. Reinehr, A. Weber, C.S. Reiner, A.E. Kremer, H. Petrowsky, P.-A. Clavien, B. Müllhaupt); University of Zurich, Zurich (R. Mita, F. Grimm, P. Deplazes, S. von Felten); Cantonal Hospital Zug, Zug, Switzerland (A. Schweiger)

Main Article

Table 3

Characteristics of patients who died because of AE, University Hospital Zurich, Zurich, Switzerland, 1973–2022*

ID Year diag Age, y/sex Stage Symp Comp Surgery Time to surgery, mo† Aim BMZ Time to BMZ† Survival time, mo† Direct cause of death
1 1973 26/M IV Yes None Yes 37 Palliative, with biliodigestive anastomosis Yes‡ 94 384 Biliocutaneous fistula, recurrent biliary infections, secondary biliary cirrhosis
2 1975 57/M IV Yes Vascular Yes 0 Curative Yes 80 238 Retroperitoneal recurrence, total IVC occlusion, GI hemorrhage
3 1975 54/F IV Yes None NA NA NA Yes 77 104 Cerebral AE manifestation
4 1978 68/F II Yes Biliary Yes 0 Palliative, with biliodigestive anastomosis Yes 0 35 Recurrent biliary infections, secondary biliary cirrhosis
5 1979 44/F IIIa Yes Vascular NA NA NA Yes 0 281 ERCP for pancreatitis, decompensation, peritonitis
6 1980 61/F IV Yes Biliary NA NA NA Yes 0 133 Secondary biliary cirrhosis
7 1982 67/M IV Yes Vascular NA NA NA Yes 0 159 Variceal bleeding
8 1983 64/F IIIb Yes Biliary NA NA NA Yes 0 53 Cholangitis with liver abscess
9 1983 47/F II Yes None Yes 0 Palliative Yes 0 233 Progressive disease, secondary surgery, postoperative multiorgan failure
10 1988 67/M IIIa Yes Biliary Yes 0 Palliative Yes 1 149 PTCD for cholangitis
11 2001 48/M IV Yes None Yes 0 Palliative, nonhepatic Yes 0 193 Cerebral AE manifestation
12 2001 56/F IIIb Yes Vascular NA NA NA Yes 0 187 Liver failure because of portal and liver vein thrombosis
13 2017 60/F IV Yes Biliary NA NA NA Yes 0 70 PTCD for cyst infection with rupture and peritoneal dissemination

*AE, alveolar echinococcosis; BMZ, benzimidazole drug therapy; comp, complications at diagnosis; diag, diagnosed; ERCP, endoscopic retrograde cholangiopancreaticography; ID, identification number; IVC, inferior vena cava; PTCD, percutaneous transhepatic cholangiography and drainage; symp, symptoms at diagnosis; surg, surgery; yod, year of diagnosis. †Time after diagnosis. ‡Discontinued after 195 months because of intolerance (95 months before death).

Main Article

1These first authors contributed equally to this article.

Page created: March 11, 2025
Page updated: April 22, 2025
Page reviewed: April 22, 2025
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