Disclaimer: Early release articles are not considered as final versions. Any changes will be reflected in the online version in the month the article is officially released.
Volume 31, Number 7—July 2025
Dispatch
Environmental Exposures Relative to Locally Acquired Hansen Disease, United States
Danielle Chaney
, Jennifer Breiman, and Jessica K. Fairley
, Jennifer Breiman, and Jessica K. Fairley
Table 1
Clinical characteristics from chart review of local and immigrant cases in study of environmental exposures in suspected locally acquired Hansen disease, United States*
| Variable | Local cases, n = 13 | Immigrant cases, n = 42 | p value† | Odds ratio (95% CI) |
|---|---|---|---|---|
| Mean age at time of diagnosis, y (SD) |
62 (+11) |
36 (+13) |
<0.005 |
NA |
| Sex | 0.88 | 1.71 (0.36–11.24) | ||
| F | 3 (23) | 14 (33) | NA | NA |
| M | 10 (77) | 27 (64) | NA | NA |
| Unknown/not available |
0 (0) |
1 (2) |
NA |
NA |
| Type of disease | 1.00 | 1.11 (0.21–5.01) | ||
| Paucibacillary | 4 (31) | 12 (29) | NA | NA |
| Multibacillary |
9 (69) |
30 (71) |
NA |
NA |
| Had leprosy reaction | 0.032 | 4.23 (1.13–17.14) | ||
| Y | 5 (39) | 30 (71) | NA | NA |
| N | 8 (62) | 11 (26) | NA | NA |
| Unknown | 0 (0) | 1 (2) | NA | NA |
*Values are no. (%) except as indicated. NA, not applicable. †2-sided p value was calculated by either t-test, χ2 test, or mid-P exact test (for an expected value <5) as appropriate, comparing immigrant cases to local cases as the reference.
Page created: June 04, 2025
Page updated: June 18, 2025
Page reviewed: June 18, 2025
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.