Volume 31, Number 7—July 2025
Dispatch
Environmental Exposures Relative to Locally Acquired Hansen Disease, United States
Danielle Chaney
, Jennifer Breiman, and Jessica K. Fairley
, Jennifer Breiman, and Jessica K. Fairley
Table 1
Clinical characteristics from chart review of local and immigrant cases in study of environmental exposures in suspected locally acquired Hansen disease, United States*
| Variable | Local cases, n = 13 | Immigrant cases, n = 42 | p value† | Odds ratio (95% CI) |
|---|---|---|---|---|
| Mean age at time of diagnosis, y (SD) |
62 (+11) |
36 (+13) |
<0.005 |
NA |
| Sex | 0.88 | 1.71 (0.36–11.24) | ||
| F | 3 (23) | 14 (33) | NA | NA |
| M | 10 (77) | 27 (64) | NA | NA |
| Unknown/not available |
0 (0) |
1 (2) |
NA |
NA |
| Type of disease | 1.00 | 1.11 (0.21–5.01) | ||
| Paucibacillary | 4 (31) | 12 (29) | NA | NA |
| Multibacillary |
9 (69) |
30 (71) |
NA |
NA |
| Had leprosy reaction | 0.032 | 4.23 (1.13–17.14) | ||
| Y | 5 (39) | 30 (71) | NA | NA |
| N | 8 (62) | 11 (26) | NA | NA |
| Unknown | 0 (0) | 1 (2) | NA | NA |
*Values are no. (%) except as indicated. NA, not applicable. †2-sided p value was calculated by either t-test, χ2 test, or mid-P exact test (for an expected value <5) as appropriate, comparing immigrant cases to local cases as the reference.
Page created: June 04, 2025
Page updated: June 25, 2025
Page reviewed: June 25, 2025
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