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Volume 31, Number 8—August 2025

Research Letter

Severe Fever with Thrombocytopenia Syndrome Acquired through Dog Bite, South Korea

Uh Jin Kim1, Hae Seong Jeong1, Keon Kim1, Ahrang Lee, Minji Kim, Sarah Kim, Sung Un Shin, Seung-Ji Kang, Sook In Jung, Hyungjun Kwak, Woong-bin Ro, Choon-Mee Kim, Dong-Min Kim2, and Kyung-Hwa Park2Comments to Author 
Author affiliation: Chonnam National University Hospital, Gwangju, South Korea (U.J. Kim, H.S. Jeong, A. Lee, M. Kim, S. Kim, S.U. Shin, S.-J. Kang, S.I. Jung, K.-H. Park); Chonnam National University Medical School, Gwangju (U.J. Kim, S.-J. Kang, S.I. Jung, K.-H. Park); Chonnam National University College of Veterinary Medicine, Gwangju (K. Kim, W. Ro); Gwangsan-gu Public Health Center, Gwangju (H. Kwak); Chosun University College of Medicine (C.-M. Kim, D.-M. Kim); Chosun University Hospital, Gwangju (D.-M. Kim)

Main Article

Figure

Phylogenetic analysis of SFTSV small (321 bp) (A), medium (477 bp) (B), and large (696 bp) (C) segments from human patient and dog, South Korea. Clustal X version 2.1 (http://www.clustal.org/clustal2) was used to construct the phylogenetic trees by using neighbor-joining with 1,000 bootstrap replicates. Genotypes of SFTSV are labeled (a, b, d, e, f). BLASTn (https://blast.ncbi.nlm.nih.gov) analysis revealed and nucleotide identity with reference SFTSV strain MF094812 of 99.44% (534/537) for the patient sample and 99.45% (541/544) for the dog sample; nucleotide identity with reference SFTSV strain MF094735 was 99.62% (785/788) for the patient sample and 99.63% (802/805) for the dog sample. The large segment nested PCR results showed 100% identity between the 2 samples. Scale bar indicates number of nucleotide substitutions per site. SFTSV, severe fever with thrombocytopenia syndrome virus.

Figure. Phylogenetic analysis of SFTSV small (321 bp) (A), medium (477 bp) (B), and large (696 bp) (C) segments from human patient and dog, South Korea. Clustal X version 2.1 (http://www.clustal.org/clustal2) was used to construct the phylogenetic trees by using neighbor-joining with 1,000 bootstrap replicates. Genotypes of SFTSV are labeled (a, b, d, e, f). BLASTn (https://blast.ncbi.nlm.nih.gov) analysis revealed and nucleotide identity with reference SFTSV strain MF094812 of 99.44% (534/537) for the patient sample and 99.45% (541/544) for the dog sample; nucleotide identity with reference SFTSV strain MF094735 was 99.62% (785/788) for the patient sample and 99.63% (802/805) for the dog sample. The large segment nested PCR results showed 100% identity between the 2 samples. Scale bar indicates number of nucleotide substitutions per site. SFTSV, severe fever with thrombocytopenia syndrome virus.

Main Article

1These first authors contributed equally to this article.

2These senior authors contributed equally to this article.

Page created: July 09, 2025
Page updated: July 18, 2025
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