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Volume 32, Number 10—October 2026
Synopsis
Systematic Review and Meta-analysis of Group B Streptococcus Rectovaginal Colonization Rates and Serotype Distribution among Pregnant Women, Asia-Pacific Region, 2014–2025
Zheng Quan Toh
, Lien Anh Ha Do, Darren Suryawijaya Ong, Claire von Mollendorf1, and Fiona M. Russell1
, Lien Anh Ha Do, Darren Suryawijaya Ong, Claire von Mollendorf1, and Fiona M. Russell1
Table 2
Antimicrobial drug resistance rates for group B Streptococcus isolates in study of rectovaginal colonization rates and serotype distribution among pregnant women, Asia-Pacific region, 2014–2025*
| Antimicrobial drugs | No. (%) studies reporting AMR† | No. isolates tested | % AMR rate, median (range) |
|---|---|---|---|
| Aminoglycosides | |||
| Amikacin/gentamicin |
2 (6.7) |
74 |
73.2 (46.4–100) |
| Amphenicols | |||
| Chloramphenicol |
9 (26.5) |
6596 |
9.2 (2.6–52.4) |
| β-lactams | |||
| Ampicillin | 16 (53.3) | 6521 | 0 (0–2.0) |
| Penicillin |
27 (90.0) |
10474 |
0 (0–2.9) |
| Carbapenems | |||
| Meropenem |
6 (20.0) |
3903 |
0 (0–2.6) |
| Cephalosporins | |||
| Cefepime | 3 (10.0) | 3776 | 2.6 (0–7.1) |
| Cefotaxime | 15 (50.0) | 5078 | 0 (0–6.7) |
| Cefazolin |
1 (3.3) |
189 |
0 |
| Fluoroquinolones | |||
| Ciprofloxacin | 4 (13.3) | 613 | 8.8 (3.3–67.4) |
| Levofloxacin |
20 (66.7) |
8919 |
26.9 (0–68.4) |
| Lincosamides | |||
| Clindamycin |
29 (96.7) |
10812 |
35.7 (0–77.1) |
| Glycopeptides | |||
| Vancomycin | 22 (73.3) | 9461 | 0 (0–3.3) |
| Teicoplanin |
1 (3.3) |
25 |
0 |
| Macrolides | |||
| Azithromycin | 2 (6.7) | 132 | 69.4 (51.3–87.5) |
| Clarithromycin | 2 (6.7) | 132 | 64.3 (50–78.6) |
| Erythromycin | 29 (96.7) | 10348 | 40.7 (5.2–78.6) |
| Telithromycin |
1 (3.3) |
56 |
3.6 |
| Oxazolidinone | |||
| Linezolid |
8 (26.7) |
1710 |
0 (0–0.8) |
| Streptogramin | |||
| Quinupristin |
1 (3.3) |
509 |
0.2 |
| Tetracyclines | |||
| Doxycycline | 2 (6.7) | 74 | 46.2 (35.7–56.7) |
| Minocycline | 1 (3.3) | 28 | 56.7 |
| Tetracycline | 14 (46.7) | 7714 | 77.7 (19.3–90.0) |
*AMR, antimicrobial drug resistance. †N = 30. Countries included in studies reporting AMR: Australia (n = 1); Bangladesh (n = 1); China (n = 10); Hong Kong, China (n = 1); India (n = 3); Indonesia (n = 1); Japan (n = 2); Taiwan (n = 3); Thailand (n = 1); South Korea (n = 3); Sri Lanka (n = 3); and Vietnam (n = 1).
1These authors contributed equally to this article.
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