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Disclaimer: Early release articles are not considered as final versions. Any changes will be reflected in the online version in the month the article is officially released.

Volume 32, Number 10—October 2026

Synopsis

Early Action Review of Detection, Notification, and Response Timeliness during Cross-Border Bundibugyo Virus Disease Outbreak, Uganda, 2026

Joshua KayiwaComments to Author , Mudarshiru Bbuye, Ritah Atuhaire, Doreen Nyakato, Mathew Tut, Bayad Nozad, Jovan Baryamujura, Bernard Lubwama, Solome Okware, Pamela Kajumba, Grace Akello, Bonny Kintu, Rebecca Kahunde, Dativa Aliddeki, Motuma Guyassa, Lydia Nakiire, Felix Ocom, Paul Mbaka, Peter Elyanu, Allan Muruta, Atek Kagirita, and Charles Olaro
Author affiliation: National Public Health Emergency Operations Centre, Ministry of Health, Kampala, Uganda (J. Kayiwa, M. Bbuye, R. Atuhaire, D. Nyakato, J. Baryamujura, B. Lubwama, P. Kajumba, G. Akello, F. Ocom, A. Kagirita); Africa Centres for Disease Control and Prevention, Addis Ababa, Ethiopia (M. Tut, D. Aliddeki); UK Health Security Agency, London, UK (B. Nozad, M. Guyassa); World Health Organization, Kampala, Uganda (S. Okware); Department of Integrated Epidemiology, Surveillance and Public Health Emergencies, Ministry of Health, Kampala (B. Kintu, A. Muruta); National Health Laboratory and Diagnostic Services, Ministry of Health, Kampala (R. Kahunde); Baylor Foundation Uganda, Kampala (L. Nakiire, P. Elyanu); Ministry of Health, Kampala (P. Mbaka, C. Olaro)

Main Article

Table 3

Bottlenecks and actions by pillar from early action review of detection, notification, and response timeliness during cross-border Bundibugyo virus disease outbreak, Uganda, 2026*

Pillar and bottlenecks Immediate action Timeline Long-term action
Pillar: Coordination
Response: implementation of a few response activities outside pillar-specific structures Formalize partner activity reporting through pillar coordination structures Immediate
Response: limited integration of mental health and psychosocial services within the response structure, contributing to initial responder fatigue and burnout
Provide an occupational health and welfare package for all responders
Immediate and continuous

Pillar: Surveillance
Detection: Vuura PoE lacked routine screening beyond 6 PM Install prefabricated screening units at all gazetted PoEs to enable and sustain continuous screening of travelers regardless of travel time Immediate Fast-track approval/designation of permanent PoE human resources; construct permanent PoE infrastructure
Response: mortality surveillance not routinely implemented under nonresponse settings Disseminate mortality surveillance guidelines, including standardizing reporting and digitalizing routine data tools Immediate and continuous Enhance training for mortality surveillance for all healthcare workers and disseminate appropriate data tools
Detection: late escalation of the initial community signal by a community leader Member of Parliament, which slightly delayed signal verification and investigation Continued engagement with community leaders, including parliamentarians, on the basic principles of community-based surveillance Immediate and continuous Continued sensitization of community leaders in the basic principles of community-based surveillance
Detection: health workers had a low index of suspicion because cases had nonclassical symptoms of EVD Conduct refresher training for health workers to strengthen clinical suspicion and reinforce surveillance and response protocols Immediate and continuous
Detection: limited cross-border surveillance information-sharing between DRC and Uganda
Periodic engagement with DRC surveillance teams to promote transparency in sharing cross-border surveillance information, especially for the current BVD outbreak and other infectious diseases
Continuous
Operationalize the existing signed MoUs to institutionalize routine cross-border collaborations, including surveillance zones, joint investigations and response simulation exercises, and quarterly PopCAB meetings.
Pillar: Laboratory
Response: suboptimal use of e-LIS, driven by an initial lack of user accounts and inadequate training
Use RRTs at national and subnational levels for on-site and virtual e-LIS training; fast-track the ICT pathway to activate missing user accounts within 48 h of activation
Immediate

Pillar: Case Management
Detection: low index of suspicion among healthcare workers, leading to insufficient use of IPC measures and delayed notification or referral in private facilities Massive distribution of job aids with clear case definitions and triage and screening protocols. Immediate and continuous Continuous medical education sessions at healthcare facility level to include revised case definitions and screening protocols
Response: unavailability of functional isolation and holding spaces in most private facilities
Engage private facilities to allocate isolation and holding spaces within their premises
Immediate and continuous
Strengthen subnational decentralization of functional isolation and treatment units in all RRHs
Pillar: Risk Communication and Community Engagement
Response: suboptimal community engagement during the early phases of the response, which led to limited uptake of response interventions Joint deployment of Risk Communication and Community Engagement teams Immediate and continuous
Response: limited funding for initial IEC material printing and scale-up
Leverage partnership with the private sector for IEC material printing and distribution


Pillar: WASH
Response: low literacy levels among some waste handlers, limiting efficient WASH uptake
Conduct refresher training for all waste handlers on effective WASH principles
Immediate and continuous

Pillar: Logistics
Response: dependence on central emergency stock acquisition and mobilization, which contributed to initial delays in emergency procurement activation Maintain minimum emergency stock levels for EVD and other viral hemorrhagic fevers at national and regional PHEOCs/RRHs Immediate and continuous Institutionalize an emergency supply-chain activation protocol with expedited, digitized approval procedures
Response: suboptimal real-time tracking of outbreak commodities and supplies at district and regional levels Quarterly inventory checks of emergency commodities at the subnational level Quarterly
Response: parallel commodity mobilization and incomplete logistics visibility, mostly fueled by infrastructure and utility failures
Establish an institutionalized, consolidated national logistics stock, pipeline, and distribution tracker integrating government and partner commodities
Continuous
Formalize logistics coordination and reporting requirements for all response pillars during IMS activation; strengthen ETU infrastructure resilience through preventive maintenance of utilities, oxygen systems, generators, and isolation facilities
Pillar: Strategic Information, Research and Innovation
Response: limited interoperability among the multiple pillar-specific reporting systems Strengthen interoperability and orient all pillars on approved response systems; ensure reporting compliance Immediate and continuous
Response: occasional server downtime and unavailability of online data-capture systems, which delayed some response reporting mechanisms Strengthen server stability; ensure a backup internet solution; institutionalize URL whitelisting for all outbreak systems Immediate and continuous Install a backup internet ISP and functional power backup at the MoH data center

*BVD Bundibugyo virus disease; DRC, Democratic Republic of the Congo; e-LIS, electronic laboratory information system; ETU, Ebola treatment unit; EVD, Ebola virus disease; ICT, information and communication technologies; IEC, information, education, and communication; IMS, incident management system; ISP, internet service provider; MoH, Ministry of Health; MoU, memorandum of understanding; PHEOC, Public Health Emergency Operations Centre; PoE, point of entry; PopCAB, Population Connectivty Across Borders; RRH, regional referral hospital; RRT, rapid response team; URL, Uniform Resource Locator; WASH, Water, Sanitation and Hygiene.

Main Article

Page created: August 11, 2026
Page updated: September 01, 2026
Page reviewed: September 01, 2026
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