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Volume 32, Number 11—November 2026

Synopsis

Predictors and Patterns of Metastatic Candidozyma auris Infection, Spain, 2016–2024

Pedro Suarez-Urquiza1, Alba Ruiz-Gaitán1Comments to Author , Eva Calabuig, María Tasias, Víctor García Bustos, Ignacio Moreno, María Ángeles Ferre, Ana María Moret, Juan Frasquet, Patricio Favier, Javier Pemán, Maria Jesus Castaño-Aroca, Paula Muñoz Brell, Mónica Gordon, Maria Dolores Gomez-Ruiz, and Miguel Salavert-Lleti
Author affiliation: Hospital Universitari i Politècnic La Fe, Valencia, Spain (P. Suarez-Urquiza, A. Ruiz-Gaitán, E. Calabuig, M. Tasias, V. García Bustos, I. Moreno, M.Á. Ferre, A.M. Moret, J. Frasquet, P. Favier, J. Pemán, M.J. Castaño-Aroca, P. Muñoz Brell, M. Gordon, M.D. Gomez-Ruiz, M. Salavert-Lletí); Instituto de Investigación Sanitaria La Fe, Valencia (P. Suarez-Urquiza, A. Ruiz-Gaitán, E. Calabuig, M. Tasias, V. García Bustos, J. Frasquet, P. Favier, J. Pemán, P. Muñoz Brell, M. Gordon, M.D. Gomez-Ruiz, M. Salavert-Lletí); Universitat de València, Valencia (E. Calabuig)

Main Article

Table 5

Antifungal susceptibility of Candidozyma auris isolates from patients with and without metastatic infection, Spain, 2016–2024*

Antifungal drug p value Metastatic infection absent
 Metastatic infection present
MIC50, mg/L MIC90, mg/L MIC50, mg/L MIC90, mg/L
Amphotericin B 0.521 0.5 1 0.5 1
Fluconazole 0.949 256 256 256 256
Itraconazole 0.440 0.25 0.5 0.125 0.5
Voriconazole 0.501 2 4 2 4
Caspofungin 0.416 0.06 0.125 0.06 0.25
Anidulafungin 0.192 0.125 0.25 0.125 0.25
Micafungin 0.853 0.06 0.125 0.06 0.125
Posaconazole 0.528 0.06 0.25 0.125 0.25
Isavuconazole 0.280 0.25 0.5 0.25 2

*MIC50, MIC inhibiting 50% of C. auris isolates; MIC90, MIC inhibiting 90% of C. auris isolates.

Main Article

1These authors contributed equally to this work and are co–first authors.

Page created: September 05, 2026
Page updated: October 14, 2026
Page reviewed: October 14, 2026
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