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Volume 32, Number 12—December 2026

Dispatch

Mayaro Virus Emergence and Genetic Dynamics, Peru

Lester J. Perez, Austin Hodges, Katherine Torres, Kenn Forberg, Sonja Weiss, Julie Yamaguchi, Maximillian Mata, Alonso Cruz-Echevarría, Diana Cubas, Freddy Alava, Dionicia Gamboa, Joseph M. Vinetz, Michael G. BergComments to Author , and Gavin A. Cloherty
Author affiliation: Abbott Laboratories, Abbott Park, Illinois, USA (L.J. Perez, A. Hodges, K. Forberg, S. Weiss, J. Yamaguchi, M. Mata, M.G. Berg, G.A. Cloherty); Abbott Pandemic Defense Coalition, Abbott Park (L.J. Perez, A. Hodges, K. Forberg, S. Weiss, J. Yamaguchi, M. Mata, M.G. Berg, G.A. Cloherty); Universidad Peruana Cayetano Heredia, Lima, Peru (K. Torres, A. Cruz-Echevarría, D. Cubas, F. Alava, D. Gamboa, J.M. Vinetz); Universidad Peruana Cayetano Heredia, Iquitos, Peru (F. Alava, D. Gamboa, J.M. Vinetz); Yale University, New Haven, Connecticut, USA (J.M. Vinetz)

Main Article

Figure 3

Phylodynamic analysis of emergence, lineage fitness, and explicit landscape dynamics of Mayaro virus lineages. A) Time-scaled maximum clade credibility tree displaying temporal emergence of Mayaro virus strains with tMRCA and 95% HPD intervals for the root and the internal clades of interest. 95% HPD intervals bars for all nodes are shown in Appendix Figure 2. A Bayesian Skyride plot of effective population size over time overlaid to illustrate fluctuations in genetic diversity. Red indicates the tMRCAs of the sequences reported in this study. B) Discrete phylogeographic analysis mapping of Mayaro virus spread across Latin America and the Caribbean; node colors indicate inferred country of origin. Red arrows indicate putative origin for the cluster of the strains reported in this study. C) Time-stamped phylogeny with lineages identified on the basis of index dynamics (inset shows estimation of the relative fitness of each lineage). HPD, highest posterior density; L2, lineage 2; L3, lineage 3; tMRCA, time to most recent common ancestor.

Figure 3. Phylodynamic analysis of emergence, lineage fitness, and explicit landscape dynamics of Mayaro virus lineages. A) Time-scaled maximum clade credibility tree displaying temporal emergence of Mayaro virus strains with tMRCA and 95% HPD intervals for the root and the internal clades of interest. 95% HPD intervals bars for all nodes are shown in Appendix Figure 2. A Bayesian Skyride plot of effective population size over time overlaid to illustrate fluctuations in genetic diversity. Red indicates the tMRCAs of the sequences reported in this study. B) Discrete phylogeographic analysis mapping of Mayaro virus spread across Latin America and the Caribbean; node colors indicate inferred country of origin. Red arrows indicate putative origin for the cluster of the strains reported in this study. C) Time-stamped phylogeny with lineages identified on the basis of index dynamics (inset shows estimation of the relative fitness of each lineage). HPD, highest posterior density; L2, lineage 2; L3, lineage 3; tMRCA, time to most recent common ancestor.

Main Article

Page created: September 05, 2026
Page updated: October 27, 2026
Page reviewed: October 27, 2026
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