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Volume 32, Supplement –Summer 2026
SUPPLEMENT ISSUE
Other
Monkeypox Virus Surveillance in Wastewater, North Carolina, USA, October 2023–May 2025
Nicole L. Snyder
, Thomas Clerkin, Sarah H. Koenigsberg, Mara B. Tate, Ty L. Lautenschlager, Justin Albertson, Emma L. Doran, Erica F. Wilson, Rachel T. Noble, Virginia T. Guidry, and Ariel R. Christensen
, Thomas Clerkin, Sarah H. Koenigsberg, Mara B. Tate, Ty L. Lautenschlager, Justin Albertson, Emma L. Doran, Erica F. Wilson, Rachel T. Noble, Virginia T. Guidry, and Ariel R. Christensen
Table 2
Diagnostic performance metrics of wastewater monitoring in study of mpox surveillance in wastewater, North Carolina, USA, October 2023–May 2025*
| Study | TP | FP | TN | FN | Sensitivity, % (95% CI) | Specificity, % (95% CI) | PPV, % (95% CI) | NPV, % (95% CI) |
|---|---|---|---|---|---|---|---|---|
| Detections above LOD and trace detections | 15 | 32 | 627 | 127 | 10.6 (6.5–16.7) | 95.1 (93.2–96.5) | 31.9 (20.4–46.2) | 83.2 (80.3–85.7) |
| Detections above LOD only | 2 | 15 | 644 | 140 | 1.4 (3.9–49.9) | 97.7 (96.3–98.6) | 11.8 (3.3–34.3) | 82.1 (79.3–84.7) |
*FN, false negative; FP, false positive; LOD, limit of detection; NPV, negative predictive value; PPV, positive predictive value; TN, true negative; TP, true positive.
Abbreviations:
Page created: July 14, 2026
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