Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link

Volume 32, Number 4—April 2026

Research Letter

Seroepidemiologic Study of Oropouche Virus, Amazonas State, Brazil, 2015–2016

Julia Forato1, Gabriel C. Scachetti1, Bárbara B. Salgado, Carolina M.L. Singh, Nadielle C. Pereira, Renato dos Santos Reis, William M. de Souza, José Luiz Proenca-Modena2, and Pritesh Lalwani2Comments to Author 
Author affiliation: University of Campinas, Campinas, Brazil (J. Forato, G.C. Scachetti, J.L. Proenca-Modena); Fiocruz Amazônia, Manaus, Brazil (B.B. Salgado, C.M.L. Singh, N.C. Pereira, P. Lalwani); Universidade Federal do Amazonas, Manaus (B.B. Salgado, C.M.L. Singh, N.C. Pereira, R. dos S. Reis, P. Lalwani); University of Kentucky, Lexington, Kentucky, USA (W.M. de Souza)

Main Article

Figure 2

Serosurvey of Oropouche virus in Coari and Manaus municipalities, Amazonas state, Brazil, 2015–2016. A) Percentage of serum samples positive for neutralizing antibodies for OROV per municipality. Error bars indicate 95% CIs. B) Box plot showing the distribution of PRNT90 titers of serum samples by municipality. Solid black horizontal line represents the median, box upper and lower limits represent the 75th and 25th percentiles, and whiskers represent minimum and maximum values. Dashed line represents LOD. Dots represent individual healthy volunteers. LOD, limit of detection; NAb, neutralizing antibodies; OROV, Oropouche virus; PRNT90, 90% plaque reduction neutralization test.

Figure 2. Serosurvey of Oropouche virus in Coari and Manaus municipalities, Amazonas state, Brazil, 2015–2016. A) Percentage of serum samples positive for neutralizing antibodies for OROV per municipality. Error bars indicate 95% CIs. B) Box plot showing the distribution of PRNT90 titers of serum samples by municipality. Solid black horizontal line represents the median, box upper and lower limits represent the 75th and 25th percentiles, and whiskers represent minimum and maximum values. Dashed line represents LOD. Dots represent individual healthy volunteers. LOD, limit of detection; NAb, neutralizing antibodies; OROV, Oropouche virus; PRNT90, 90% plaque reduction neutralization test.

Main Article

1These authors contributed equally to this article.

2These senior authors contributed equally to this article.

Page created: February 27, 2026
Page updated: April 15, 2026
Page reviewed: April 15, 2026
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external