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Volume 32, Number 6—June 2026
Emerging Infection Networks Letter
Increase in blaNDM among Carbapenemase-Producing, Carbapenem-Resistant Enterobacterales, United States, 2016–2023
Uzma Afroz Ansari
, Davina Campbell, Joshua M. Brandenburg, Nadezhda Duffy, Julian E. Grass, Alice Y. Guh, Joseph D. Lutgring, Christopher A. Elkins, Maria Karlsson, Amy S. Gargis, and HAIC MuGSI Working Group1
, Davina Campbell, Joshua M. Brandenburg, Nadezhda Duffy, Julian E. Grass, Alice Y. Guh, Joseph D. Lutgring, Christopher A. Elkins, Maria Karlsson, Amy S. Gargis, and HAIC MuGSI Working Group1
Table
Frequency of blaNDM by species from study investigating increase in blaNDM among CP-CRE, United States, 2016–2023*
| Year | Total no. CP-CRE isolates | No. (%) isolates |
|||
|---|---|---|---|---|---|
| All blaNDM† | Escherichia coli | Klebsiella spp. | Enterobacter cloacae complex | ||
| 2016 |
111 |
6 (5.4) |
2 (1.8) |
4 (3.6) |
0 |
| 2017 |
149 |
9 (6.0) |
5 (3.4) |
4 (2.7) |
0 |
| 2018 |
166 |
12 (7.2) |
6 (3.6) |
5 (3.0) |
1 (0.6) |
| 2019 |
145 |
24 (16.6) |
13 (9.0) |
9 (6.2) |
2 (1.4) |
| 2020 |
134 |
22 (16.4) |
13 (9.7) |
6 (4.5) |
3 (2.2) |
| 2021 |
153 |
32 (20.9) |
17 (11.1) |
10 (6.5) |
5 (3.3) |
| 2022 |
181 |
61 (33.7) |
27 (14.9) |
23 (12.7) |
11 (6.1) |
| 2023 |
249 |
99 (39.8) |
57 (22.9) |
29 (11.6) |
13 (5.2) |
| Total | 1288 | 265 (20.6) | 140 (10.9) | 90 (7.0) | 35 (2.7) |
*Data are updated for accuracy and may differ from online reports (accessed 2025 Aug 19) (5). CP-CRE, carbapenemase-producing, carbapenem-resistant Enterobacterales. †Includes isolates carrying blaNDM (n = 245), dual mechanism blaNDM+blaOXA-48 (n = 17) and blaNDM+blakpc (n = 3).
References
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1HAIC MuGSI Working Group members are listed at the end of this article.
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