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Volume 32, Number 6—June 2026

Research Letter

Neisseria gonorrhoeae Sequence Type 16676 in Disseminated Infections, Minnesota, USA, 2025

Daniel EvansComments to Author , Allison LaPointe, Christine Peel, Khalid Bo-Subait, Elizabeth Dufort, Jenell Stewart, John Kaiyalethe, Bradley Craft, Matthew Plumb, Bonnie Weber, Laura Bohnker-Voels, Kelly Pung, Alyssa Mondelli, Jacob Garfin, Sarah Namugenyi, Paula Snippes-Vagnone, M. Elizabeth Gyllstrom, Kathryn Como-Sabetti, and Ruth Lynfield
Author affiliation: Health Protection Bureau, Minnesota Department of Health, St. Paul, Minnesota, USA (D. Evans, A. LaPointe, C. Peel, K. Bo-Subait, E. Dufort, J. Kaiyalethe, B. Craft, M. Plumb, B. Weber, L. Bohnker-Voels, K. Pung, A. Mondelli, J. Garfin, S. Namugenyi, P. Snippes-Vagnone, M.E. Gyllstrom, K. Como-Sabetti, R. Lynfield); University of Minnesota, Minneapolis, Minnesota, USA (J. Stewart); Hennepin Healthcare, Minneapolis (J. Stewart)

Main Article

Figure 2

Reference-based pairwise single-nucleotide polymorphism (SNP) matrix of 26 Neisseria gonorrhoeae sequence type 16676 infections from study of outbreak of N. gonorrhoeae sequence type 16676 among disseminated infections, Minnesota, USA, 2025. Genomes numbered 1–14 (red) are from Minnesota disseminated gonococcal infection isolates in 2025. Genomes numbered 15–26 (blue) represent the other genomes grouped in the same National Center for Biotechnology Information Pathogen Detection cluster (PDS000214546.4.) in October 2025. SNP calls were clustered and displayed using Morpheus software (https://software.broadinstitute.org/morpheus). SNP calls <20 are highlighted in grayscale. Genome number 7 was used as an internal reference for calling SNPs with the Dryad version 3.0 pipeline (7).

Figure 2. Reference-based pairwise single-nucleotide polymorphism (SNP) matrix of 26 Neisseria gonorrhoeae sequence type 16676 infections from study of outbreak of N. gonorrhoeae sequence type 16676 among disseminated infections, Minnesota, USA, 2025. Genomes numbered 1–14 (red) are from Minnesota disseminated gonococcal infection isolates in 2025. Genomes numbered 15–26 (blue) represent the other genomes grouped in the same National Center for Biotechnology Information Pathogen Detection cluster (PDS000214546.4.) in October 2025. SNP calls were clustered and displayed using Morpheus software (https://software.broadinstitute.org/morpheus). SNP calls <20 are highlighted in grayscale. Genome number 7 was used as an internal reference for calling SNPs with the Dryad version 3.0 pipeline (7).

Main Article

References
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