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Volume 32, Number 8—August 2026

Research Letter

Novel Parvovirus in Pigs Associated with Exophthalmos and Erythema, the Netherlands

Tijs J. TobiasComments to Author , René Renzhammer, Charlotta A.J. Roos, Marrina G. Schuttert, Paul Waijers, Carmijn B. Meulenbroek, Karin Junker, José L. van Wilgen, Claudie Herbrink, Rick Elbert, Christiaan Sanderman, Eveline Willems, Remco Dijkman, and Erhard van der Vries
Author affiliation: Royal GD, Deventer, the Netherlands (T.J. Tobias, R. Renzhammer, C.A.J. Roos, K. Junker, J.L. van Wilgen, C. Herbrink, R. Elbert, C. Sanderman, E. Willems, R. Dijkman, E. van der Vries); Utrecht University, Utrecht, the Netherlands (T.J. Tobias); De Varkenspraktijk, Someren, the Netherlands (M.G. Schuttert, P. Waijers); De Oosthof Dierenartsen, Nijverdal, the Netherlands (C.B. Meulenbroek)

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Figure 2

In situ hybridization from study of multifarm outbreak of novel parvovirus in pigs associated with exophthalmos and erythema, the Netherlands, 2024. A) Hepatocytes with red coloring depict Protoparvovirus nucleic acids, indicating focal presence of viral nucleic acids in nuclei of hepatocytes. In the center, viral DNA is present with 2 excentric foci in a cell nucleus, indicative of viral DNA presence in a cell in mitosis (brightfield scan of histology slide, 40× objective magnification [0,19 µm/pixel]). B) In situ hybridization of swine testicular cell line infected with protoparvovirus. Original magnification 10×10.

Figure 2. In situ hybridization from study of multifarm outbreak of novel parvovirus in pigs associated with exophthalmos and erythema, the Netherlands, 2024. A) Hepatocytes with red coloring depict Protoparvovirus nucleic acids, indicating focal presence of viral nucleic acids in nuclei of hepatocytes. In the center, viral DNA is present with 2 excentric foci in a cell nucleus, indicative of viral DNA presence in a cell in mitosis (brightfield scan of histology slide, 40× objective magnification [0,19 µm/pixel]). B) In situ hybridization of swine testicular cell line infected with protoparvovirus. Original magnification 10×10.

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Page created: May 26, 2026
Page updated: July 06, 2026
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