Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link

Volume 32, Number 9—September 2026

Research

Posttuberculosis Consequences on Tuberculosis Prevention Effectiveness and Cost-effectiveness among New Immigrants, Canada

Aotikuer Ainiwaer, Aashna Uppal, Kevin Schwartzman, Kamila Romanowski, Sarah K. Brode, James C. Johnston, and Jonathon R. CampbellComments to Author 
Author affiliation: McGill University, Montreal, Quebec, Canada (A. Ainiwaer, K. Schwartzman, J.R. Campbell); University of Oxford, Oxford, UK (A. Uppal); Research Institute of the McGill University Health Centre, Montreal (K. Schwartzman, J.R. Campbell); McGill International TB Centre, Montreal (K. Schwartzman, J.R. Campbell); University of British Columbia, Vancouver, British Columbia, Canada (K. Romanowski, J.C. Johnston); British Columbia Centre for Disease Control, Vancouver (K. Romanowski, J.C. Johnston); University of Toronto, Toronto, Ontario, Canada (S.K. Brode); University Health Network, Toronto (S.K. Brode)

Main Article

Table 3

Effects of post-tuberculosis consequences on incremental outcomes between intervention and status quo*

Incremental outcomes between status quo and intervention Acute TB consequences only, referent Post-TB elevated risk for death Post-TB
persistent disease		 Post-TB healthcare costs All post-TB consequences
Absolute incremental cost, millions, 2023 CAD 19.4 (4.1–38.0) 19.4 (4.1–38.0) 19.4 (4.1–38.0) 18.7 (3.3–37.3) 18.7 (3.3–37.3)
Relative incremental cost compared with no post-TB consequences
 1.0
 1.0
 1.0
 0.96 (0.87–0.99)
 0.96 (0.87–0.99)
Absolute incremental QALY 82 (28–124) 138 (76–198) 131 (65–200) 82 (28–124) 186 (109–267)
Relative incremental QALY ratio compared with no post-TB consequences
 1.0
 1.7 (1.3–3.0)
 1.7 (1.2–2.7)
 1.0
 2.4 (1.6–4.4)
Absolute incremental TB-related deaths −12 (−15 to −7) −25 (−33 to −18) −12 (−15 to −7) −12 (−15 to −7) −25 (−33 to −18)
Relative incremental TB deaths ratio compared with no post-TB consequences
 1.0
 2.2 (1.6–3.0)
 1.0
 1.0
 2.2 (1.6–3.0)
ICER $235,088 $140,146 $147,595 $227,340 $100,742
<$50,000, % 3 5 5 3 11
<$100,000, % 8 27 25 9 53
<$150,000, % 21 59 54 24 81

*Incremental outcomes refer to the difference between intervention and status quo per 400,000 persons. Values are (95% uncertainty range). ICER, incremental cost-effectiveness ratios; QALY, quality adjusted life year; TB, tuberculosis.

Main Article

Page created: July 30, 2026
Page updated: August 26, 2026
Page reviewed: August 26, 2026
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external