Volume 5, Number 3—June 1999
Perspective
Iron Loading and Disease Surveillance
Eugene D. Weinberg
Table 1
Iron loading in specific tissues and increased risk for disease
| Tissue type | Disease |
|---|---|
| Alveolar macrophages | Pulmonary neoplasia and infection |
| Anterior pituitary | Gonadal and growth dysfunction |
| Aorta; carotid and coronary arteries | Atherosclerosis |
| Colorectal mucosa | Adenoma, carcinoma |
| Heart | Arrhythmia, cardiomyopathy |
| Infant intestine | Botulism, salmonellosis, sudden death |
| Joints | Arthropathy |
| Liver | Viral hepatitis, cirrhosis, carcinoma |
| Macrophages | Intracellular infections |
| Pancreas | Acinar and beta cell necrosis, carcinoma |
| Plasma and lymph | Extracellular infections |
| Skeletal system | Osteoporosis |
| Skin | Leprosy, melanoma |
| Soft tissue | Sarcoma |
| Substantia nigra | Parkinson's disease |
Page created: December 10, 2010
Page updated: December 10, 2010
Page reviewed: December 10, 2010
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.